Blood Pressure and Left Ventricular Mass (Lvm) Changes Following Renal Transplantation in Patients Receiving Calcineurin Inhibitors

Barr, Caroline; Buchalter, Maurice B.; Morris‐Stiff, Gareth; Singh, Jeffrey M.; Quiroga, Isabel; Baboo, R.; Stockdill, H.; Baboolal, Keshwar; Jurewicz, W. A.

doi:10.1097/00007890-199905150-00317

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Major Causes Of Mortality1

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“…The fall in LV mass was significantly associated with a fall in blood pressure. These findings have been confirmed by our own data (Barr et al . 1999) showing a significant improvement (Wilcoxon ranks test P = 0.045) in the LV mass index in the first year following transplantation.…”

Section: Major Causes Of Mortalitysupporting

confidence: 91%

Strategies for ensuring effective surveillance in post‐transplant patients: practical organization and clinical evaluation

Jurewicz

Miles

2004

Evaluation Clinical Practice

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Results of renal transplantation have improved steadily over the years. This article reviews the current status of patient and graft survival and discusses major causes of mortality and renal allograft failure. Review of recent literature demonstrates that the traditional enemies of transplantation, acute rejection and opportunistic infections are no longer major problems facing transplantation. Chronic graft nephropathy and death with functioning graft due to cardiovascular disease are the main challenges in the current era. An impact of an early graft thrombosis, recurrent renal disease and post-transplant malignancies are also reviewed. Chronic graft nephropathy is examined in a context of differences between two calcineurin inhibitors, cyclosporin microemulsion and tacrolimus. Strategies of post-transplant surveillance are suggested.

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Section: Major Causes Of Mortalitysupporting

confidence: 91%