Blood Parathyrin and Mineral Metabolism Dynamics. A clinical analyze

Radu, Lucreţiu; Cârșote, Mara; Galateanu, Ancuta Augustina Gheorghisan; Preda, Smaranda Adelina; Calborean, Veronica; Stanescu, Radu; Gheorman, Victor; Albulescu, Dana Maria

doi:10.37358/rc.18.10.6619

Cited by 21 publications

(26 citation statements)

References 6 publications

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Section: Bariatric Surgery and Vitamin Dmentioning

confidence: 99%

“…Bariatric surgery has an explosive use during the last years (7,8,9). Even it saves lives, some complications (that are difficult to be considered "iatrogenic") are identified especially in relationship with nutrients and vitamins loss (7,8,9). Bone might also suffer since 75% of the patients have hypovitaminosis D and require lifelong vitamin D substitution with high doses (7,8,9).…”

Section: Bariatric Surgery and Vitamin Dmentioning

confidence: 99%

“…Even it saves lives, some complications (that are difficult to be considered "iatrogenic") are identified especially in relationship with nutrients and vitamins loss (7,8,9). Bone might also suffer since 75% of the patients have hypovitaminosis D and require lifelong vitamin D substitution with high doses (7,8,9). Otherwise, two thirds of untreated patients with vitamin D replacements might manifest clinical aspects of tetania (7,8,9).…”

Section: Bariatric Surgery and Vitamin Dmentioning

confidence: 99%

“…Bone might also suffer since 75% of the patients have hypovitaminosis D and require lifelong vitamin D substitution with high doses (7,8,9). Otherwise, two thirds of untreated patients with vitamin D replacements might manifest clinical aspects of tetania (7,8,9). In these cases both of our patients experienced post-operatory low vitamin D levels.…”

Section: Bariatric Surgery and Vitamin Dmentioning

confidence: 99%

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From skin infections to bariatric surgery in patients with endocrine tumours

Şandru¹,

Valea²,

Albu³

et al. 2019

Ro Med J.

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Obesity is associated with multiple complications like cardiovascular, oncologic, including skin infections potentially with a more severe evolution than in subjects with normal weight. We aim is to introduce two cases of females who initially presented with skin infections associating obesity and two different types of endocrine tumours; both of them underwent bariatric surgery. One case of a young female who had acne and menses anomalies was confirmed with macroprolactinoma and treated with cabergoline with menses control. For obesity she had bariatric surgery with weight and acne control but associating long term hypovitaminosis D. The second case is a menopausal woman with metabolic syndrome and different persistent skin infections in association with features of cardio-metabolic anomalies which were confirmed as adrenal Cushing's syndrome and referred for unilateral adrenalectomy. The improvement of mentioned parameters was not associated with obesity control so bariatric surgery was done. She suffered a shoulder fracture and she was confirmed with osteoporosis (a lumbar T-score of -3.3 SD). The values of 25-hydroxyvitamin D remained normal only under oral replacement with vitamin D supplements and zolendronic acid was added. Obesity underlines heterogeneous aspects including dermatological, metabolic, cardiovascular and endocrine conditions; some of them are dramatically improved after bariatric surgery, yet not hipovitaminosis D and osteoporosis especially in menopausal women. The prolactin excess, Cushing's disease or just obesity itself may cause repeated skin infections or acne. abbreviations BMI = body mass index DXA = Dual-Energy X-Ray Absorptiometry SD = standard deviation RefeRenCeS

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Section: Bariatric Surgery and Vitamin Dmentioning

confidence: 99%

Section: Bariatric Surgery and Vitamin Dmentioning

confidence: 99%

Section: Bariatric Surgery and Vitamin Dmentioning

confidence: 99%

Section: Bariatric Surgery and Vitamin Dmentioning

confidence: 99%

See 2 more Smart Citations

From skin infections to bariatric surgery in patients with endocrine tumours

Şandru¹,

Valea²,

Albu³

et al. 2019

Ro Med J.

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“…Fail of PTH levels control through vitamin D replacement makes necessary another surgical intervention because of the risk of chronic complications in addition to the general morbidities caused by chronic kidney disease including osteoporosis (9,10). As useful tools for the practitioners in order to evaluate to bone status we mention the bone turnover markers, the levels of bone hormones like PTH as well as central DXA (Dual-Energy X-Ray Absorptiometry) (11)(12)(13).…”

Section: Introductionmentioning

confidence: 99%

Tertiary hyperparathyroidism – location dilemma

Cârșote¹,

Albu²,

Şandru³

et al. 2019

Ro Med J.

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Renal failure is associated with numerous complications including cardiovascular, dermatological, neurological, surgical and endocrine. Hypovitaminosis D induces secondary hyperparathyroidism and long term effects are represented by autonomous stimulation of the parathyroid glands (tertiary hyperparathyroidism). Fail of PTH (parathyroid hormone) levels control through vitamin D replacement makes necessary a surgical intervention because of the risk of chronic complications in addition to the general morbidities caused by chronic kidney disease including osteoporosis. Our aim is to present a case of an adult woman with a very long history of renal failure complicated with tertiary hyperparathyroidism and osteoporosis. The clue of the case is the difficult localisation of PTH source after total parathyroidectomy was previously done in order to remove it and timing of re-intervention. There is a challenge to adequately locate the parathyroid remnants after a prior glands removal and a skilled surgeon is still the best "tool". However, the risk of surgery in a cases with multiple complications is very high so it is preferable a pre-operatory localisation. The neck ultrasound is the most accessible tool offering a good accuracy if there is no mediastinal localisation and also the combination with parathyroid scintigram increases the rate of detection. abbreviations BMD = bone mineral density DXA = Dual-Energy X-Ray Absorptiometry PTH = parathormone SD = standard deviation

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