Blood parameters of wistar albino rats fed processed tropical sickle pod (Senna obtusifolia) leaf meal-based diets

Abstract

A feeding trial was conducted for 28 d to evaluate the effects of feeding albino rats with processed Senna obtusifolia leaf meal (SOLM) based diets. Five experimental diets were compounded to contain 0% and 20% each of the sun-dried, boiled, fresh fermented, and boiled and fermented SOLM-based diets designated as T1, T2, T3, T4, and T5, respectively. A total of 90 young albino rats with initial weight of 13.52–14.48 g were randomly allocated to the dietary treatments in a completely randomized design with three replicates of six rats each. The hematological parameters revealed nonsignificant (P > 0.05) difference except for the rats fed the sun-dried SOLM-based diet, which had the lowest packed cell volume (34%), red blood cell (5.32 × 106/µ/L), and hemoglobin (13.67 g/dL). The hematological values recorded were, however, within the normal reference ranges. The biochemical indices were also not significantly (P > 0.05) different. The total protein, creatinine, alanine aminotransferase, and total bilirubin recorded were within the ranges of 71.50–77.73 g/L, 1.03–1.23 mg/dL, 20.67–24.37 µ/L, and 10.13–11.67 µ/L, respectively. It was concluded that the different processed SOLM-based diets had no adverse effects on the blood parameters of the albino rats and are, therefore, recommended for feeding albino rats.

Production, Nutritional Value and Toxicity of Kawal, a Fermented Product from the Leaves of Cassia obtusifolia (L.): A Review

“…This allowed the authors to conclude that the inclusion of 20% fermented leaves of C. obtusifolia had no adverse effects on the immune system, liver and kidneys of rats. The difference in the results of Augustine et al [43] in Nigeria with those of Yagi et al [40] as well as Suliman et al [11] in Sudan would be due to the fermentation conditions. Augustine et al [43] performed a 9-day fermentation under laboratory conditions, while the authors from Sudan had based their studies on the kawal whose fermentation followed different stages of the technological production process.…”

“…The difference in the results of Augustine et al [43] in Nigeria with those of Yagi et al [40] as well as Suliman et al [11] in Sudan would be due to the fermentation conditions. Augustine et al [43] performed a 9-day fermentation under laboratory conditions, while the authors from Sudan had based their studies on the kawal whose fermentation followed different stages of the technological production process. The number of days of production of the kawal (14 to 25 days) as well as the regular mixing every three days are enough to create this difference.…”

“…It should be noted that the fermentation did not take place under the same conditions as those of kawal. Indeed, in Nigeria, Augustine et al [43] fed albino rats with 20% C. obtusifolia leaves that had undergone the following treatments: sun-dried, boiled, fermented fresh, boiled and fermented. Rats fed with the leafless control diet of C. obtusifolia showed higher food consumption.…”