Blood neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios are independent prognostic factors for surgically resected gastrointestinal stromal tumors

Evaluation of Hemocytometer Parameters as Potential Biomarkers in Benign Multinodular Goiter and Papillary Thyroid Carcinoma

“…The relationship between the inflammatory and noninflammatory diseases such as acute appendicitis, varicocele, cancers, coronary artery diseases, idiopathic pulmonary arterial hypertension, and tinnitus and some of the hemocytometer parameters are investigated in recent years (1)(2)(3). Among these hemocytometer parameters, neutrophil/lymphocyte ratio (NLR), MPV, platelet/lymphocyte ratio (PLR), platelet indices, and platelet distribution width (PDW) are the most studied ones.…”

“…This relationship is related to the systemic inflammatory process. It is observed that systemic inflammatory is closely associated with all phases of cancer (1). A variety of white blood cell (WBC) and platelet indices such as MPV and PLR are also associated with the clinicopathological characteristics and survival of many cancers (4,5).…”

Uygun maliyetli ve kolay ulaşılabilir bir belirteç olarak platelet/lenfosit oranı

“…PLR has been evaluated in patients with several diseases including chronic inflamatory diseases, malignancies, myeloproliferative disorders, cardiovasculer diseases and infectious diseases [1][2][3][4][5][6][7][8][9][10][11][12][13] .…”

“…Furthermore, elevated PLR levels have been shown in patients with several diseases such as cancer (e.g., prostate, colorectal, cervical, ovarian, malignant pleural mesothelioma and surgically resected gastrointestinal stromal tumors), peripheral artery disease, hypertension, coronary artery disease, limb ischemia, poor prognostic myocardial infraction, infective endocarditis, exacerbation of chronic obstructive pulmonary disease (COPD), systemic lupus erythematosus (SLE), psoriasis vulgaris, Behçet's syndrome, pseudoexfoliation syndrome [1][2][3][4][5][6][7][8][9][10][11][12][13] . On the contrary, reduced PLR levels have been reported in patients with obstructive sleep apnea syndrome (OSAS) 6 .…”

“…PLR has been described as an indipendent predictor of in-hospital mortality in patients with infective endocarditis 2 , an independent risk factor for morbidity and mortality after coronary arter bypass grafting 12 , and an independent prognostic factor for surgically resected gastrointestinal stromal tumors 10 , or useful for predicting the prognosis of in patients with pseudoexfoliation syndrome and progression to pseudoexfoliation glaucoma 7 , malignant pleural mesothelioma 8 and recurrent cervical cancer 9 . And PLR more than 107 has been suggested to be independent predictor of non-dipper hypertension 11 .…”