Blood metabolome profiling for patient stratification and assessment of disease severity among Asian Indian patients with Type 2 diabetes mellitus
Sneha Rana,
Vivek Mishra,
Prajval Nakrani
et al.
Abstract:Introduction: Type 2 diabetes mellitus is a heterogeneous disease with broader metabolic perturbation beyond hyperglycemia, resulting in varied prognoses. Clustering analyses using clinical features have identified at least four sub-types with differing disease progression among patients with type 2 diabetes. Additionally, patients are at risk of developing complications such as diabetic kidney disease (DKD), the early stages of which are clinically silent. Metabolomics offers a comprehensive understanding of … Show more
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