Blood loss and endocrine responses in hypotensive anaesthesia with sodium nitroprusside and nitroglycerin for mandibular osteotomy

Comparison of Esmolol to Nitroglycerine in Controlling Hypotension During Nasal Surgery

“…They also suggested that discontinuation of the hypotensive agents resulted in a significant increase in MAP in the SNP group. Increases in CAD at 30 and 60 min were reported upon NTG application in a different study [17]. When comparing CAD control values, the decrease in the hypotensive and compilation period was 35% and 18% in the esmolol and 23% in the NTG groups.…”

“…Pilli et al [16] reported that there was no significant difference in the arterial blood gas samples in hypotensive anesthesia achieved with esmolol (28.7% reduction in SAP). In their study comparing NTG and SNP with normo-tensive anesthetic procedures in mandibular osteotomies, Yoshikawa et al [17] demonstrated a similar reduction in the PaO 2 values in the blood gas samples taken from of all three groups 60 minutes post-surgery. They suggested that the reductions in the PaO 2 value were not affected by the administration of both drugs and that this could be explained by the ventilation/perfusion mismatch associated with artificial ventilation during anesthetic administration.…”

“…Yoshikawa et al [17] reported that the target MAP 60-70 mmHg during an NTG-accompanied mandibular osteotomy was achieved at 1-5 μg/kg/min by an infusion rate of 13.3±1.5 min. Degoute et al [8] reported that the target SAP (80 mmHg) in tympanoplasty procedures was achieved in 53.3±4.4 seconds with esmolol (210±33 μg/kg/min).…”

Acute normovolemic hemodilution in patients undergoing head and neck surgery: a prospective randomized trial

“…Placing the patient in an anti-Trendelenburg position is useful as well. Various drugs are used to induce hypotension during surgery, such as propranolol, nicardipine, sodium nitroprusside and nitroglycerin [7][8][9]. Studies that compared drug protocols have failed to find significant difference in outcome [10,11].…”

Induced hypotension in the management of acute hemobilia during therapeutic ERCP in a patient with portal biliopathy (with videos)

“…13 Agents used successfully alone include inhalation anesthetics, sodium nitroprusside, nitroglycerin, and agents used in spinal anesthesia. 13,14 Nitroglycerin has been shown to be effective in lowering the intravascular esophageal variceal pressure in grade II and grade III varices, 15 and nitroglycerin-induced controlled hypotension has been used for management of bleeding during endoscopic sphincterotomy. 16 We present here a case of acute hemobilia in which nitroglycerininduced controlled hypotension caused temporary disappearance of ICDV and allowed completion of therapeutic ERCP in a case of portal hypertensive biliopathy.…”