Blood Lactate in the Prognosis of Various Forms of Shock

Vítek, V.; Cowley, R. Adams

doi:10.1097/00000658-197102000-00021

Cited by 133 publications

(53 citation statements)

References 10 publications

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“…L actic acidosis is related to tissue hypoperfusion and hypoxia in critically ill patients with sepsis 1) or after cardiogenic shock [2][3][4] and is associated with a poor prognosis when left untreated. Under anaerobic conditions, cellular metabolism converts pyruvate to lactate.…”

mentioning

confidence: 99%

The Incidence, Risk Factors, and Outcomes of Hyperlactatemia after Heart Transplantation

2018

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SummaryHyperlactatemia (HL) is associated with tissue hypoperfusion during cardiac surgery, which results in postoperative morbidity and mortality among patients undergoing cardiopulmonary bypass surgery. The aim of this study was to determine the incidence, risk factors, and outcome of HL after heart transplantation (HTx) in one of the largest Japanese single-center cohorts. We retrospectively studied the lactate levels in 49 patients who underwent HTx at the University of Tokyo Hospital from August 1, 2010 to November 30, 2015. All of the patients were over 20 years of age. Arterial blood samples were analyzed during the operation and until 24 hours after surgery. Twenty-nine patients (59.2%) had HL after intensive-care unit admission. At 24 hours after surgery, the lactate levels of all patients had recovered to the normal range. A multivariate analysis showed that the total ischemic time of the donor heart (odds ratio [OR], 1.0176; 95% confidence interval [CI], 1.0004-1.0375; P = 0.0444) and the duration of preoperative left ventricular assist device (LVAD) support (OR, 0.9977; 95% CI, 0.9952-0.9997; P = 0.0218) were risk factors for HL. Pulmonary complications were noted in 24.1% of the patients with high lactate values but in none of the patients without HL (P = 0.0182); however, there were no cases of hospital death, and the length of hospital stay did not differ to a statistically significant degree between HL groups (P = 0.719). Although HL after HTx was common, it appeared to be transient and benign. Donor heart ischemia and the duration of preoperative LVAD support were associated with HL after transplantation.(Int Heart J 2018; 59: 81-86)

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confidence: 99%

The Incidence, Risk Factors, and Outcomes of Hyperlactatemia after Heart Transplantation

2018

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“…Numerosos estudios han establecido el uso del lactato como marcador diagnóstico, terapéutico y pronóstico [11][12][13][14][15][16] . Los niveles de lactato al ingreso están fuertemente asociados a pronóstico 12 , empero, la medición de niveles seriados tiene mayor valor que una medición única aislada 17 .…”

Section: Utilidad De La Medición De Lactato En El Servicio De Urgenciaunclassified

Shock séptico en pediatría II: Enfoque actual en el diagnóstico y tratamiento

et al. 2013

Rev. chil. pediatr.

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“…Plasma lactate was chosen because it is widely considered to be itself a measure of the severity of injury (Broder & Weil 1964, Peretz et al 1965, Vitek & Cowley 1971.…”

Section: Improvement Of Iss -First Attemptmentioning

confidence: 99%

Measuring the Severity of Injury

Yates¹

1992

Yearbook of Intensive Care and Emergency Medicine

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Blood Lactate in the Prognosis of Various Forms of Shock

Cited by 133 publications

References 10 publications

The Incidence, Risk Factors, and Outcomes of Hyperlactatemia after Heart Transplantation

The Incidence, Risk Factors, and Outcomes of Hyperlactatemia after Heart Transplantation

Shock séptico en pediatría II: Enfoque actual en el diagnóstico y tratamiento

Measuring the Severity of Injury

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