Blood Hemolytic Activity and Acute Toxicity of Saponins extract from Lepudium aucheri Boiss.

Abstract

The hemolytic activity process was applied to erythrocytes by an analyst, as well as the lysis of erythrocytes resulted in a positive test result. The L. aucheri Boiss. extracts are high in triterpenoids saponins, according to the findings. Both extracts were used in acute toxicity in vivo research on four groups of rats (six rats in each group). After 72 hours of treatment with various concentrations of terpenoids saponins extracts (25, 50, and 100 mg/kg BW), no mortality was detected in the rats of the trials. This demonstrated that both extracts are harmless when taken orally.