Blood FOLR3 methylation dysregulations and heterogeneity in non-small lung cancer highlight its strong associations with lung squamous carcinoma
Yunhui Qu,
Xiuzhi Zhang,
Rong Qiao
et al.
Abstract:Background
Non-small cell lung cancer (NSCLC) accounts for the vast majority of lung cancers. Early detection is crucial to reduce lung cancer-related mortality. Aberrant DNA methylation occurs early during carcinogenesis and can be detected in blood. It is essential to investigate the dysregulated blood methylation markers for early diagnosis of NSCLC.
Methods
NSCLC-associated methylation gene folate receptor gamma (FOLR3) was selected from an Ill… Show more
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