Blood Flow Restriction Training Applied With High-Intensity Exercise Does Not Improve Quadriceps Muscle Function After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial

Curran, Mike; Bedi, Asheesh; Mendias, Christopher L.; Wojtys, Edward M.; Kujawa, Megan; Palmieri-Smith, Riann M.

doi:10.1177/0363546520904008

Cited by 43 publications

(95 citation statements)

References 41 publications

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“…All studies included in the review were RCTs [25][26][27][28][29][30][31][32][33][34] published from 2003 onwards. It should be noted that the studies from Hughes et al [33] 2018 and Hughes et al [34] 2019 are two reports from the same study.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…It should be noted that the studies from Hughes et al [33] 2018 and Hughes et al [34] 2019 are two reports from the same study. Two studies were conducted in Brazil [25,29], four in the USA [26][27][28]30], two in the UK [33,34], one in Norway [31] and one in Japan [32].…”

Section: Study Characteristicsmentioning

confidence: 99%

“…In total, 166 patients received a BFR training intervention and 198 received a non-BFR training intervention. A population with two types of pathology were studied, where five studies included patients with KOA [25][26][27][28][29] (204 participants) and the other five studies included patients with ACL reconstruction [30][31][32][33][34] (160 participants). For the KOA population, the duration of the intervention was four weeks [27,28], six weeks [29] and 12 weeks [25].…”

Section: Participantsmentioning

confidence: 99%

“…For the KOA population, the duration of the intervention was four weeks [27,28], six weeks [29] and 12 weeks [25]. In the ACL reconstruction population, the duration of intervention was two weeks [31], eight weeks [30,33,34] and 16 weeks [32].…”

Section: Participantsmentioning

confidence: 99%

“…Low-load training at 30% 1MR [27,28] or moderate load at 60% was used [26], although one study did not specify the percentage of low load [32]. Three studies applied high-load training at 70% of 1MR [29,30,34]. Furthermore, two studies presented two control groups [25,33]: one study [25] applied a load of 80% in one group and 30% in the other, and the other study [33] applied 70% of 1MR in one group and 30% in the other group in which BFR was also applied in healthy subjects.…”

Section: Interventionmentioning

confidence: 99%

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Comparison of Blood Flow Restriction Training versus Non-Occlusive Training in Patients with Anterior Cruciate Ligament Reconstruction or Knee Osteoarthritis: A Systematic Review

Álvarez

Santamaría

Fernández-Matías

et al. 2020

JCM

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Patients undergoing anterior cruciate ligament (ACL) reconstruction and patients suffering from knee osteoarthritis (KOA) have been shown to have quadriceps muscle weakness and/or atrophy in common. The physiological mechanisms of blood flow restriction (BFR) training could facilitate muscle hypertrophy. The purpose of this systematic review is to investigate the effects of BFR training on quadriceps cross-sectional area (CSA), pain perception, function and quality of life on these patients compared to a non-BFR training. A literature research was performed using Web of Science, PEDro, Scopus, MEDLINE, Dialnet, CINAHL and The Cochrane Library databases. The main inclusion criteria were that papers were English or Spanish language reports of randomized controlled trials involving patients with ACL reconstruction or suffering from KOA. The initial research identified 159 publications from all databases; 10 articles were finally included. The search was conducted from April to June 2020. Four of these studies found a significant improvement in strength. A significant increase in CSA was found in two studies. Pain significantly improved in four studies and only one study showed a significant improvement in functionality/quality of life. Low-load training with BFR may be an effective option treatment for increasing quadriceps strength and CSA, but more research is needed.

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Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Section: Participantsmentioning

confidence: 99%

Section: Participantsmentioning

confidence: 99%

Section: Interventionmentioning

confidence: 99%

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Comparison of Blood Flow Restriction Training versus Non-Occlusive Training in Patients with Anterior Cruciate Ligament Reconstruction or Knee Osteoarthritis: A Systematic Review

Álvarez

Santamaría

Fernández-Matías

et al. 2020

JCM

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Quadriceps muscle size changes following exercise in anterior cruciate ligament reconstructed limbs: A systematic review

Dutaillis

Timmins

Lathlean

2021

Translational Sports Med

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Anterior cruciate ligament (ACL) injury and reconstructive surgery is known to cause long-term negative impacts on quadriceps muscle size. With the known link between reduced muscle size and the health and functioning of the knee joint, it is important rehabilitation programs aim to restore quadriceps mass as safely and quickly as possible. However, a comprehensive review of interventions investigating the impact of training interventions on quadriceps muscle size in ACL-reconstructed individuals has yet to be undertaken. Therefore, this article systematically reviews the evidence investigating training interventions that aim to improve quadriceps size in ACL-reconstructed individuals. A literature search was performed in MEDLINE, SPORTDiscus, CINAHL, and Web of Science. Observational and experimental studies investigating training interventions impact on quadriceps muscle size in ACL-reconstructed individuals were included. Risk-of-bias assessment (Downs and Black) was completed on included studies, data was extracted, and a best evidence synthesis was undertaken. 718 articles were returned in the initial search; following screening, six articles were included in this review. Results from the best evidence synthesis suggest there is moderate evidence for eccentrically biased training to increase quadriceps size. Both traditional resistance training and blood flow restriction training showed conflicting results for improving quadriceps size. However, the results for traditional resistance training and blood flow restriction training may have been limited by differing imaging methods across included studies. This review highlights the positive changes in quadriceps size seen following traditional, eccentrically biased and blood flow restriction exercise interventions in ACL-reconstructed limbs, despite the limited number of studies. Further work is needed to identify and optimize the best practice for hypertrophic training in these individuals.

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Blood Flow Restriction Training and Return to Play Following Knee Surgery

Hughes,

Patterson

2023

Knee Arthroscopy and Knee Preservation Surgery

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Blood Flow Restriction Training Applied With High-Intensity Exercise Does Not Improve Quadriceps Muscle Function After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial

Cited by 43 publications

References 41 publications

Comparison of Blood Flow Restriction Training versus Non-Occlusive Training in Patients with Anterior Cruciate Ligament Reconstruction or Knee Osteoarthritis: A Systematic Review

Comparison of Blood Flow Restriction Training versus Non-Occlusive Training in Patients with Anterior Cruciate Ligament Reconstruction or Knee Osteoarthritis: A Systematic Review

Quadriceps muscle size changes following exercise in anterior cruciate ligament reconstructed limbs: A systematic review

Blood Flow Restriction Training and Return to Play Following Knee Surgery

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