Blood flow patterns estimation in the left ventricle with low-rate 2D and 3D dynamic contrast-enhanced ultrasound

Chen, Peiran; Sloun, Ruud J. G. van; Turco, Simona; Wijkstra, Hessel; Filomena, Domenico; Agati, Luciano; Houthuizen, Patrick; Mischi, Massimo

doi:10.1016/j.cmpb.2020.105810

Cited by 8 publications

(4 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Numerous vortex characteristics and flow parameters have been investigated, such as location and area of the vortex, as well as kinetic energy, energy loss, and circulation [1][2][3][4][5][6][7]. While changes in these parameters have been linked to cardiac dysfunction and specific cardiovascular diseases, including cases of Congenital Heart Disease (CHD), their clinical use remains limited [8].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Investigation of a novel intracardiac flow parameter using blood speckle imaging

Jensen¹

2023

J Clin Images Med Case Rep

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

“…In a healthy LV, the vortex is stable and ellipse-shaped [5][6][7][8][9]. This vortex becomes increasingly unstable and circular with LV adaptation, which is believed to induce further remodeling of cardiac tissue.…”

Section: Introductionmentioning

confidence: 99%

Investigation of a novel intracardiac flow parameter using blood speckle imaging

Jensen¹

2023

J Clin Images Med Case Rep

View full text Add to dashboard Cite

show abstract

“…Doppler echocardiography, in its most classical version, yields only one component of the velocity vectors (Jensen et al 2016), the one parallel to the direction of the ultrasound wave. To overcome this limitation, several ultrasound imaging techniques have been developed for a 2D vector depiction of the intracardiac flow, such as echo-PIV (echographic particle image velocimetry) by contrast-enhanced echocardiography (Kheradvar et al 2010, Chen et al 2021, blood speckle tracking (Fadnes et al 2014, Daae et al 2021, or iVFM (intraventricular vector flow mapping) (Garcia et al 2010. The echo-PIV technique requires the intravenous injection of microbubbles, which is not compatible with a routine clinical use.…”

Section: Introductionmentioning

confidence: 99%

“…Some of the methods used were derived from 2D techniques. Feasibility of echo-PIV to obtain a volumetric view of intraventricular flow has been described in vitro and in vivo (Sengupta et al 2012, Voorneveld et al 2020, Chen et al 2021. Gomez et al recovered the 3D flow (Gomez et al 2013(Gomez et al , 2015 by spatio-temporally registering three or four color Doppler volumes acquired from different acoustic windows.…”

Section: Introductionmentioning

confidence: 99%

Full-volume three-component intraventricular vector flow mapping by triplane color Doppler

Vixège¹,

Bérod²,

Courand³

et al. 2022

Phys. Med. Biol.

View full text Add to dashboard Cite

Objective. Intraventricular vector flow mapping (iVFM) is a velocimetric technique for retrieving two-dimensional velocity vector fields of blood flow in the left ventricular cavity. This method is based on conventional color Doppler imaging, which makes iVFM compatible with the clinical setting. We have generalized the iVFM for a three-dimensional reconstruction (3D-iVFM). Approach. 3D-iVFM is able to recover three-component velocity vector fields in a full intraventricular volume by using a clinical echocardiographic triplane mode. The 3D-iVFM problem was written in the spherical (radial, polar, azimuthal) coordinate system associated to the six half-planes produced by the triplane mode. As with the 2-D version, the method is based on the mass conservation, and free-slip boundary conditions on the endocardial wall. These mechanical constraints were imposed in a least-squares minimization problem that was solved through the method of Lagrange multipliers. We validated 3D-iVFM in silico in a patient-specific CFD (computational fluid dynamics) model of cardiac flow and tested its clinical feasibility in vivo in patients and in one volunteer. Main results. The radial and polar components of the velocity were recovered satisfactorily in the CFD setup (correlation coefficients, r = 0.99 and 0.78). The azimuthal components were estimated with larger errors (r = 0.57) as only six samples were available in this direction. In both in silico and in vivo investigations, the dynamics of the intraventricular vortex that forms during diastole was deciphered by 3D-iVFM. In particular, the CFD results showed that the mean vorticity can be estimated accurately by 3D-iVFM. Significance. Our results tend to indicate that 3D-iVFM could provide full-volume echocardiographic information on left intraventricular hemodynamics from the clinical modality of triplane color Doppler.

show abstract

Vortex Formation Time is a Novel Measure for Early Detection of Diastolic Abnormalities in Adolescents with Hypertension

et al. 2023

View full text Add to dashboard Cite

Pediatric hypertension (HTN) has demonstrated an upward trend in recent years. Adolescent HTN has been linked to adult HTN, cardiovascular disease, and other health conditions. Thus, it is essential that HTN and its associated cardiac abnormalities be diagnosed and treated early to minimize lifelong adverse effects. In this study, we evaluated whether vortex formation time (VFT), a validated echocardiogram measure of left ventricular diastolic dysfunction, correlated with ambulatory blood pressure monitoring (ABPM) and HTN in adolescents. Echocardiogram data including systolic and diastolic function indices and ABPM data from 2015 to 2022 in adolescents age 13-21 years were analyzed retrospectively. We found that VFT was signi cantly lower in adolescents with HTN compared to those without (3.69 ± 1.39 vs. 4.50 ± 1.73, p = 0.02). Standard echocardiographic indices of systolic and diastolic function were similar between the two groups. Higher overall systolic blood pressure (SBP) (β = -0.01, CI -0.02, -2.2 x 10 − 3 , p = 0.02), mean wake SBP (β = -0.01, CI -0.02, -9.4 x 10 − 4 , p = 0.03) and mean sleep SBP (β = -0.01, CI -0.02, -1.2 x 10 − 3 , p = 0.03) were signi cantly associated with lower VFT.This study demonstrates that VFT correlates to ABPM data and can be used as a novel diagnostic measure of early diastolic dysfunction in adolescents with HTN.

show abstract

Blood flow patterns estimation in the left ventricle with low-rate 2D and 3D dynamic contrast-enhanced ultrasound

Cited by 8 publications

References 47 publications

Investigation of a novel intracardiac flow parameter using blood speckle imaging

Investigation of a novel intracardiac flow parameter using blood speckle imaging

Full-volume three-component intraventricular vector flow mapping by triplane color Doppler

Vortex Formation Time is a Novel Measure for Early Detection of Diastolic Abnormalities in Adolescents with Hypertension

Contact Info

Product

Resources

About