Blood Flow of the Areola and Breast Skin Flaps During Reduction Mammaplasty as Measured by Laser Doppler Flowmetry

Tracy, Charles A.; Pool, Robert; Gellis, Michael B.; Vasileff, W Kelton

doi:10.1097/00000637-199202000-00006

Cited by 12 publications

(2 citation statements)

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“…The LDF method has been used in ever-increasing applications [14], One of the main disadvantages of the technique, however, is its low spatial resolution ( -2 mm2) and the need to apply the probe directly to the tissue being studied. To obtain an accurate result with these techniques the breast tissue must be homogeneously perfused.…”

Section: Discussionmentioning

confidence: 99%

“…Breast scintigraphy by 201T1 can clearly demonstrate palpable breast cancer and also lymph node metastasis [9], but poor resolution remains a problem [10]. High resolution CT is effective for detec tion of lymph node metastasis [11], MRI offers excellent qualitative diagnosis of tumours, but detection of ultra small lesions is difficult even using contrast medium [12], Doppler ultrasound is used to study large vessel flow rath er than microcirculation [ 13], Laser Doppler flowmetry (LDF) has been widely used to investigate the pathophysiologic changes that occur in the microcirculation of the skin in patients with vascular disorders [14], The disadvantage of LDF is that it gives information about tissue perfusion only in a focal point ( -2 mm2), while the spatial vascular architecture of the breast varies greatly in the normal and diseased breast. Furthermore skin blood flow may be easily altered by the placement of an LDF probe on the surface of the skin if any pressure is exerted.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Laser Doppler Perfusion Imaging – A New Technique for Measuring Breast Skin Blood Flow

Seifalian¹,

Chaloupka²,

Parbhoo³

1995

Int J Microcirc

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Future detection of breast cancer will probably be based on tissue function such as altered vascularity and blood flow. Assessment of tumour blood flow and its pattern may be significant for prognostic prediction, and early evaluation of treatment response. An ideal method of assessment of perfusion would therefore measure a wide area of the breast without the necessity for surface contact. A possible method for achieving this ideal is the recent development of a laser Doppler imager (LDI) that creates an image of tissue perfusion. The method is based on the recording of Doppler shift caused by movements of red blood cells in the backscattered light of a laser beam that successively scans a certain tissue area. This method reflects the vascularity of overlaying skin. We have applied this technique to 101 patients, 47 normal, 25 benign, and 29 carcinoma. Our findings were correlated with breast imaging and tissue diagnosis. The mean blood flow in ‘normal’ patients was 299 ± 155 and 311 ± 157 flux ( ± SD) for right and left breast, in patients with benign breast change it was 482 ± 209 flux and in patients with carcinoma it was 711 ± 280 flux. Patients with benign breast change have higher skin blood flow than symptomatic normal patients but the highest levels have been recorded in patients with breast cancer. We believe that LDI may have an important role in improving our understanding of the physiology of the normal breast and may provide a practical method of monitoring breast skin blood flow changes in clinical situations.

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Section: Discussionmentioning

confidence: 99%