Blood cockle (Anadara granosa) supplementation to increase serum calcium level and femur growth of low-protein diet rat

Abstract

Abstract. Solang M. 2017. Blood cockle (Anadara granosa) supplementation to increase serum calcium level and femur growth of lowprotein diet rat. Nusantara Bioscience 9: 62-67. Blood cockle (Anadara granosa) contains protein, zinc and calcium. The aim of this study was to evaluate the effects of blood cockle flour supplement on serum calcium level, rat femur length and weight of rat femur on low-protein diet. The design of research used The Separate Sample Pre-Post Test Design. Forty eight Wistar male rats were randomly grouped into 2 groups, 12 rats as normal control group and 36 rats as malnourished group. After eight weeks, 4 rats from each group were sacrificed. Furthermore, 8 rats as normal control and 32 rats as malnourished group were randomly grouped. Malnourished rats were treated with blood cockle flour of 12.5%/kg diet, 25%/kg diet, and 50%/kg diet ad libitum for 8 weeks. Data analysis was performed with One Way ANOVA, LSD, Kruskal-Wallis and Mann-Whitney tests. The results of study showed that the supplementation of blood cockle flour of 12.5%/kg diet was significantly increase the serum calcium level (p=0.003), rat femur length (p=0.000) and rat femur weight (p=0.002) on low-protein diet. This study demonstrated that blood cockle flour can be used as alternative food to improve the growth of rat femurs in a malnutrition condition.

Calcium Bioavailability and Serum Calcium Level in Pregnant Rats After Administration of Milk-Based Drinks Containing Lactic Acid Bacteria

“…Albumin plays an important role in transporting calcium, which means that there is a relationship between calcium absorption and protein intake. Therefore, lowprotein diet causes lower calcium absorption; hence, the level of calcium in the blood decreases (Solang 2017). Moreover, induction Administration of MBD containing LAB did not significantly affect serum calcium level during pregnancy.…”

“…This might be due to the induction of undernutrition. Study by Solang (2017) showed that induction of undernutrition in rats by administering an 8.46% protein diet for eight weeks showed a decrease in serum calcium level by 31.4% compared to the control group given 13-15% protein for 8 weeks. Moreover, calcium level in the control group was 11.8±0.20 mg/dl (Solang 2017).…”

Pemberdayaan Masyarakat Dalam Penanganan Balita Stunting Melalui Pemanfatan Pangan Lokal Sumber Protein Dan Zink Berbasis Kerang Di Kabupaten Pohuwato Provinsi Gorontalo

“…Bahan pangan yang merupakan sumber protein alternatif dan zink diantaranya adalah kerang. Kerang darah asal Gorontalo menunjukkan mengandung protein total 27,26%, sedangkan kandungan mineral antara lain: zinc 81,16 ppm, Fe 1720,46 ppm, Cu 4,26 ppm, dan Ca 318,67 ppm (Solang et al, 2013;Solang, 2017). Kerang tersedia cukup melimpah di desa Iloheluma Kecamatan Patilanggio Kabupaten Pohuwato dan harganya terjangkau namun belum termanfaatkan secara maksimal., Pemanfaatan untuk konsumsi hanya dilakukan pada saat perayaan hari raya ketupat.…”