Blood-Cadmium in Hypertensives and Normotensives

Beevers, D. G.; Goldberg, A.; Campbell, Brian C.; Moore, Michael R.; Hawthorne, Victor M.

doi:10.1016/s0140-6736(76)91145-4

Cited by 62 publications

(21 citation statements)

References 14 publications

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“…However the precision of the present method, as determined by including a previously analysed sample in each analytical run, was good; in terms of relative accuracy, good comparability was found with established methods. Beevers et al (1976) and Ulander and Axelson (1974) reported a significant difference between the whole blood concentration of smokers and nonsmokers, which is confirmed in this communication;…”

Section: Discussionsupporting

confidence: 87%

“…Hypertension was not reported in a group of workers industrially exposed to cadmium (Cernik and Sayers, 1975). Several studies of the concentration of cadmium in whole blood or plasma of normal and hypertensive populations have since been conducted, some of which confirmed Glauser's observation (Thind and Fischer, 1976), while other studies (Beevers et al, 1976) found no elevated concentration of the trace metal in hypertensive patients.…”

Section: Annals Of Clinicalmentioning

confidence: 76%

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Significance of Blood Cadmium Concentrations in Patients with Renal Disorders or Essential Hypertension and the Normal Population

Ward¹,

Fisher

Tellez-Yudilevich

1978

Ann Clin Biochem

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Summary Cadmium concentrations in whole blood have been determined in normal control subjects, in patients with untreated essential hypertension or with treated essential hypertension, and in those with acute or chronic renal disorders. High cadmium concentrations were not found in the patients with untreated essential hypertension. Most tobacco smokers were found to have high blood cadmium concentrations. When the mean cadmium concentrations from each group of patients were compared with those of the control subjects no significant differences were found. When the four groups were divided into smokers and non-smokers, however, a significantly higher mean value was found for the non-smoking renal patients in comparison with the non-smoking normal subjects. The marked increases in blood cadmium concentration in the patients with renal disorders may be attributed to impaired excretion.

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Section: Discussionsupporting

confidence: 87%

Section: Annals Of Clinicalmentioning

confidence: 76%

Significance of Blood Cadmium Concentrations in Patients with Renal Disorders or Essential Hypertension and the Normal Population

Ward¹,

Fisher

Tellez-Yudilevich

1978

Ann Clin Biochem

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“…One o f the wor st problems concerns the measurem ent of cadm ium exposure. Man y studies estimated the exposure by measur ing cadmium in blood (77,80,124,137,138,140,141,(148)(149)(150)(151)153). The blood cadmium level is, however, not a very reliable mea sure of the cadmium body burden.…”

Section: Cadmiummentioning

confidence: 99%

“…Man y of the investigations empl oyed a "quasi case-referent" design in which sick persons (with hypertension or IHD) were compa red to health y referents (77,123,124,128,130,133,(140)(141)(142)(144)(145)(146)(147)(148)(149)(150)(151)(152)(153)(154). The se studies are called " quas i case-re ferent" becau se in reali ty they ar e crosssectional studies in which " disease" (hypertension , for exampl e) is measured simulta neously with " exposure" (for example, cadmium in blood).…”

Section: Cadmiummentioning

confidence: 99%

Cardiovascular diseases and the work environment. A critical review of the epidemiologic literature on chemical factors.

Kristensen¹

1989

Scand J Work Environ Health

199

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“…Trace metals are of interest in relation to coronary heart disease risk because lead and cadmium have been suggested to play a role in the etiology of hypertension (1)(2)(3)(4). Zinc, copper, and lithium may also be related to coronary heart disease risk (5,6).…”

Section: Introductionmentioning

confidence: 99%

Blood lead and coronary heart disease risk among elderly men in Zutphen, The Netherlands.

Kromhout

1988

Environ Health Perspect

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Information about blood lead and other coronary heart disease risk factors was coliected in 1977 among 152 men aged 57 to 76 years in the town of Zutphen, the Netherlands. Blood lead was determined by atomic absorption spectrometry. The blood lead distribution was skewed to the right.The median blood lead concentration was 167 pg/L, and the mean was 183 pg/L Blood lead levels above 300 pg/L were present among 8.6% and levels above 400 pg/L among 1.3% of the Zutphen men. Blood lead was of borderline significance to cigarette smoking. After both univariate and multivariate analyses, a significant association was found between blood lead and blood pressure. This relation was stronger for systolic than for diastolic blood pressure. Of the 141 elderly men free of coronary heart disease in 1977, 26 developed coronary heart disease between 1977 and 1985. Blood lead was not associated with coronary heart disease incidence in both univariate and multivariate analyses.

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Blood-Cadmium in Hypertensives and Normotensives

Cited by 62 publications

References 14 publications

Significance of Blood Cadmium Concentrations in Patients with Renal Disorders or Essential Hypertension and the Normal Population

Significance of Blood Cadmium Concentrations in Patients with Renal Disorders or Essential Hypertension and the Normal Population

Cardiovascular diseases and the work environment. A critical review of the epidemiologic literature on chemical factors.

Blood lead and coronary heart disease risk among elderly men in Zutphen, The Netherlands.

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