Blood-based DNA methylation study of alcohol consumption
Elena Bernabeu,
Aleksandra D Chybowska,
Jacob K. Kresovich
et al.
Abstract:Alcohol consumption is an important risk factor for multiple diseases. It is typically assessed via self-report, which is open to measurement error and bias. Instead, molecular data such as blood-based DNA methylation (DNAm) could be used to derive a more objective measure of alcohol consumption by incorporating information from cytosine-phosphate-guanine (CpG) sites known to be linked to the trait. Here, we explore the epigenetic architecture of self-reported weekly units of alcohol consumption in the Generat… Show more
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