Blood and Liver Concentrations of Vitamins A and E in Children with Cystic Fibrosis of the Pancreas

Underwood, Barbara A.; Denning, Carolyn R.

doi:10.1203/00006450-197201000-00004

Cited by 82 publications

(29 citation statements)

References 9 publications

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“…In addition, serum vE content is decreased in pancreatic-insuffi cient patients at the onset of pulmonary exacerbations ( 68 ). These results are consistent with a decrease of vE in liver ( 69 ). However, to our knowledge, the content of this vitamin in intestinal mucosa had not been addressed before.…”

Section: Discussionsupporting

confidence: 79%

Lipid mapping of colonic mucosa by cluster TOF-SIMS imaging and multivariate analysis in cftr knockout mice

Brulet

Seyer

Edelman

et al. 2010

Journal of Lipid Research

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Section: Discussionsupporting

confidence: 79%

Lipid mapping of colonic mucosa by cluster TOF-SIMS imaging and multivariate analysis in cftr knockout mice

Brulet

Seyer

Edelman

et al. 2010

Journal of Lipid Research

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“…Vitamin A deficiency may rarely lead to mucosal abnormalities or to pseudotumor cerebri [1,147]. Clinical vitamin D deficiency is rare [67], as there appears to be adequate absorption through the skin [118].…”

Section: Pancreatic Insufficiencymentioning

confidence: 99%

Cystic fibrosis

Bye¹,

Ewig²,

Quittell

1994

Lung

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While the care of cystic fibrosis (CF) patients has been mainly the province of pediatricians, great improvements in the therapy and life span of CF patients often results in their transition to care by adult physicians. In this review of CF, we begin with an overview of the epidemiology and genetics of the disease, with a discussion of the recently found ion abnormalities that lead to the clinical manifestations. This is followed by a discussion of the pathophysiology. Methods of diagnosis, ranging from the gold standard, the sweat test, to recent advances based on a greater understanding of the genetics of the disease are reviewed. This is followed by a discussion of therapy primarily geared to the treatment of the respiratory complications, as they are the most common lethal factors of the disease. We point out controversies where they exist. Newer forms of therapy such as lung transplantation are discussed, and we finish with a discussion about future therapeutic modalities, some of which are being approved as the paper is in print.

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“…It was subsequently shown that low levels of retinol-binding protein may be just as important as fat malabsorption in its aetiology. Even in the presence of low plasma vitamin A levels, a normal or increased liver concentration is found at autopsy, which suggests that there may be a problem in mobilization of vitamin A from the liver (Underwood & Denning, 1972). Among the clinical features described in CF are night blindness, conjunctival xerosis, dry thickened skin and abnormalities of bronchial mucosal epithelialization.…”

Section: Specific Nutrient Deficienciesmentioning

confidence: 99%

Nutrition in cystic fibrosis: a historical overview

Dodge

1992

Proc. Nutr. Soc.

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Blood and Liver Concentrations of Vitamins A and E in Children with Cystic Fibrosis of the Pancreas

Cited by 82 publications

References 9 publications

Lipid mapping of colonic mucosa by cluster TOF-SIMS imaging and multivariate analysis in cftr knockout mice

Lipid mapping of colonic mucosa by cluster TOF-SIMS imaging and multivariate analysis in cftr knockout mice

Cystic fibrosis

Nutrition in cystic fibrosis: a historical overview

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