Essentials • COVID-19 has been one of the largest culture-shifting phenomena of this generation. • Amid many negative impacts of COVID-19 on science, certain positives have emerged. • Positives include enhanced global interactions, time for reflection, and diversity initiatives. • We should preserve positive outcomes when returning to a post-COVID-19 world. Undoubtedly, COVID-19 has been one of the largest cultureshifting phenomena of this generation. Many countries, including Canada, Israel, Ireland, and the United States, have seen doubledigit increases in the percentage of their workforce filing unemployment insurance claims, with over 40 million people unemployed in the United States alone, due to the pandemic. 1,2 Many who are still employed are facing significant hurdles and career setbacks as they attempt to navigate budget cuts, promotion freezes, and the demands of child care (without the help of schools and daycare services). Socioeconomic disparities have been exacerbated by differential access to high-speed Internet, computers, health care, and child care. Some, though not all, reports document fewer COVID-19-related scientific publications by women compared to men, suggesting the pandemic has had a disproportionate impact on the productivity of this segment of the academic workforce. 3-6 Rapid restructuring in funding mechanisms to support scientific studies in COVID-19 may have shifted funding away from other established areas, with potentially negative repercussions for research on other diseases. COVID-19 has seamlessly brought the global economy to its knees, and simultaneously dismantled the crux of every social interaction. It has been, in essence, an endless newsreel of catastrophic proportions.