Blind but alive - congenital loss ofatoh7disrupts the visual system of adult zebrafish
Juliane Hammer,
Paul Röppenack,
Sarah Yousuf
et al.
Abstract:Purpose Vision is the predominant sense in most animal species. Loss of vision can be caused by a multitude of factors resulting in anatomical as well as behavioral changes. In mice and zebrafish, atoh7 mutants are completely blind as they fail to generate retinal ganglion cells during development. In contrast to mice, raising blind zebrafish to adulthood is challenging and this important model is currently missing in the field. Here, we report the phenotype of homozygous mutant adult zebrafish atoh7 mutants t… Show more
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