Bleomycin therapy for cystic hygroma

Orford, Jillian; Barker, Andrew; Thonell, Sven; King, P. A.; Murphy, John

doi:10.1016/0022-3468(95)90485-9

Cited by 165 publications

(112 citation statements)

References 5 publications

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“…14°' S After that several trials have been reported using bleomycin with good or excellent results in up to 88% of cases. 16,11 Bleomycin is an antibiotic known to have some antitumoral activity and also have local sclerosing effect on endothelial cells of cysts wall of lymphangioma. Intralesional Bleomycin microsphere in oil-emulsion has reported good response because it is retained for longer period of time.…”

Section: Discussionmentioning

confidence: 99%

Non surgical management of cystic lymphangioma

Rawat

Sinha

Kanojia

et al. 2006

Indian J Otolaryngol Head Neck Surg

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Section: Discussionmentioning

confidence: 99%

Non surgical management of cystic lymphangioma

Rawat

Sinha

Kanojia

et al. 2006

Indian J Otolaryngol Head Neck Surg

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“…Many previous studies have found excellent and good results in at least 60% of the cases [2,13] . Sanlialp et al also witnessed results similar to the findings in this study [6] .…”

Section: Discussionmentioning

confidence: 82%

Effectiveness of Intralesional Bleomycin Sclerotherapy for Lymphangioma in Children

Fiaz¹

2018

jmscr

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“…Desired effect of sclerosis is achieved by local action of bleomycin, which depends on availability of drug per unit surface area of the lesion. 9,10 Side effects of Bleomycin are fever, transient increase in size of the swelling, hemorrhage, leukocytosis, infection, and pulmonary fibrosis.…”

Section: Discussionmentioning

confidence: 99%

Ultrasound guided intralesional bleomycin therapy for cystic lymphangioma in childhood

Pan¹

2017

Int J Contemp Pediatr

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Background: Lymphangiomas are benign hamartomatous lymphatic tumors, characterized by multiple communicating lymphatic channels and cystic spaces. They occur in nearly all regions of the body but are most frequently seen in the neck (75%), axilla (20%), and inguinal areas (2%). This study aims to evaluate the effectiveness of intralesional bleomycin sclerotherapy in the treatment of cystic lymphangioma in children and to determine the incidence of complications in the treatment.Methods: This is a prospective study of 36 children diagnosed with cystic lymphangioma and treated with intralesional injection of bleomycin aqueous solution from 2008 to 2015.Results: Complete resolution was seen in (16/36) of lesions, (17/36) had a good response and (3/36) had a poor response. The tumour recurred in 3 patients. No other serious complications or side effects were observed.Conclusions: Intralesional bleomycin therapy was very effective in the treatment of cystic lymphangioma. Our results were comparable to other published studies. Bleomycin administered as intralesional injection was found to be safe as there was no serious complication or side effect observed in this study.

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Bleomycin therapy for cystic hygroma

Cited by 165 publications

References 5 publications

Non surgical management of cystic lymphangioma

Non surgical management of cystic lymphangioma

Effectiveness of Intralesional Bleomycin Sclerotherapy for Lymphangioma in Children

Ultrasound guided intralesional bleomycin therapy for cystic lymphangioma in childhood

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