Bleeding risk in hemophilia A and B carriers: comparison of factor levels determined using chronometric and chromogenic assays
Delphine Chiffré-Rakotoarivony,
Isabelle Diaz-Cau,
Alexandre Ranc
et al.
Abstract:Background
Predicting the bleeding risk in hemophilia A and B carriers (HAC, HBC) is challenging.
Objective
The objectives of this study were to describe the bleeding phenotype in HAC and HBC using the standardized Tosetto bleeding score (BS); to determine whether the BS correlates better with factor levels measured with a chromogenic assay than with factor levels measured with chronometric and thrombin generation assays; and to compare the results in H… Show more
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