Bleeding in carriers of hemophilia

Plug, Iris; Mauser‐Bunschoten, Eveline P.; Bröcker‐Vriends, A. H. J. T.; Amstel, Hans Kristian Ploos van; Bom, Johanna G. van der; Diemen-Homan, Joanna E. M. Van; Willemse, J.; Rosendaal, Frits R.

doi:10.1182/blood-2005-09-3879

Cited by 301 publications

(375 citation statements)

References 15 publications

(12 reference statements)

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“…It is extremely important to discriminate between severe (FVIII:C < 1 IU dL )1 ), moderate (FVIII:C between 1 and 5 IU dL ) and mild haemophilia (FVIII:C between 5 and 25 IU dL )1 ). Besides, the correct identification of patients with sub-haemophilia and carriers of haemophilia is important as these patients need to be protected against bleeding complications during surgical interventions [3]. In this review, the practical problems that arise with the laboratory diagnosis of FVIII deficiency will be discussed.…”

Section: Introductionmentioning

confidence: 99%

Diagnosis of factor VIII deficiency

Verbruggen

Meijer²,

Nováková

2008

Haemophilia

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Summary. The correct diagnosis of factor VIII deficiency and the assessment of severity of the disease are essential for a patient-tailored treatment strategy. An optimal diagnostic procedure comprises sensitive and specific screening methods and factor VIII activity assays. Different screening reagents show variable characteristics and receiver operator characteristic curves are presented showing the relation between sensitivity and specificity of eleven activated partial thromboplastin time reagents. The details of the three methods for factor VIII activity assay, onestage and two-stage assay and chromogenic assays, are discussed. The chromogenic assay seems to be more sensitive than the one-stage assay with regard to the detection of severe haemophilia. Discrepant results obtained with one-stage and two-stage assays are reviewed and discussed.

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Section: Introductionmentioning

confidence: 99%

Diagnosis of factor VIII deficiency

Verbruggen

Meijer²,

Nováková

2008

Haemophilia

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“…De manera posterior a las intervenciones en pacientes con trastornos de la coagulación, y como tratamiento alternativo a las lesiones que puede presentar el paciente, tanto en urgencias como en consulta programada, se puede realizar: enjuagues con preparado de agua destilada 200cc con una ampolla de ácido tranexamico durante el primer día, y agua destilada 500cc con ampolla de ácido tranexamico durante los días siguientes, si continúa el sangrado. Poner hielo de manera intermitente por 10 minutos (43)(44)(45)(46).…”

Section: Tratamientounclassified

Cuidado odontológico de pacientes con trastornos hereditarios de la coagulación

Cano-Franco¹,

Ortiz-Orrego²,

González-Ariza³

2017

CES odontol.

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“…Prenašalke z aktivnostjo FVIII / IX < 40 % imajo krvavitve, podobne tistim pri lahkih hemofilikih, in specifične krvavitve za ženske (menoragija, krvavitve po porodu) (253). Prenašalke z aktivnostjo faktorja 40-60 % imajo lahko večje nagnjenje h krvavitvam (256,257). Celo prenašalke z normalno aktivnostjo FVIII imajo več krvavitev v primerjavi s populacijo žensk, ki hemofilije ne prenašajo (258).…”

Section: Prenašalke Hemofilijeunclassified

Nacionalna priporočila za obravnavo bolnikov s hemofilijo

et al. 2017

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The document presents recommendations for the comprehensive treatment of patients with haemophilia in Slovenia. It enables health workers at all three levels of health care to become well-acquainted with all the possible aspects of treatment based on the best practices of major centres worldwide, and on the studies and experience of health professionals at the National Haemophilia Centre, University Medical Center Ljubljana. The document contains definitions, treatment algorithms and lists of medications with their characteristics and appropriate dosages. It specifically defines indications for the exclusive competence of the tertiary level in Ljubljana due to the actual availability of teams and laboratory options. It also contains an extensive list of the literature on haemophilia.

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Bleeding in carriers of hemophilia

Cited by 301 publications

References 15 publications

Diagnosis of factor VIII deficiency

Diagnosis of factor VIII deficiency

Cuidado odontológico de pacientes con trastornos hereditarios de la coagulación

Nacionalna priporočila za obravnavo bolnikov s hemofilijo

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