Blastomycosis‐like pyoderma: response to systemic retinoid therapy

Kobraei, Kathy B.; Wesson, Stanton K.

doi:10.1111/j.1365-4632.2010.04470.x

Cited by 11 publications

(20 citation statements)

References 8 publications

(26 reference statements)

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“…Monotherapy with systemic antibiotics usually requires longterm treatment and often fails [7,9]. Our patient's immune status was compromised by an untreated HIV infection, as well as a concurrent syphilitic infection.…”

Section: Case Reportmentioning

confidence: 97%

“…First described in 1903 as "pseudoepiteliomas cutanés, " blastomycosis-like pyoderma (BLP) is a chronic pyoderma that presents similarly to vegetating deep fungal infections [3,7]. It typically presents as one or multiple vegetating nodules and/or plaques on the extremities of middle aged to elderly adults [10].…”

Section: Discussionmentioning

confidence: 99%

“…abscesses may also be present [10]. The differential diagnosis includes blastomycosis and other deep fungal infections, halogenoderma, pemphigus vegetans, tuberculosis verrucosa cutis, pyoderma gangrenosum, mycobacterial infections, giant keratoacanthoma, and squamous cell carcinoma [2,4,[7][8][9][10][11][12]. Our patient had four of the six criteria for BLP established by Su et al In accordance with the pertinent literature, we refrained from preforming fungal serology and blood halogen level testing.…”

Section: Case Reportmentioning

confidence: 99%

“…Many systemic immune dysregulatory states have been described in patients diagnosed with BLP including leukemia, chemotherapy, malnourishment, and alcoholism [3,7]. There are cases of BLP arising at areas of local disturbance such as sun exposure, trauma and tattoo in immunocompetent persons [2,3,7].…”

Section: Introductionmentioning

confidence: 99%

“…There are cases of BLP arising at areas of local disturbance such as sun exposure, trauma and tattoo in immunocompetent persons [2,3,7].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Blastomycosis-Like Pyoderma in a Patient with Syphilis and HIV Resolving with Antibiotic Therapy

Jetter¹,

Juhl²,

Tsoukasc³

2017

J Clin Case Rep

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Blastomycosis-like pyoderma (BLP) is a rare, exaggerated, vegetative tissue reaction that occurs in patients with local or systemic immune dysregulation. Reported causes of immune compromise include human immunodeficiency virus, malnutrition, alcoholism, leukemia, immunosuppressant use, radiation therapy, and others. Nearly all cases involve an underlying, prolonged pyogenic bacterial infection. Historically monotherapy with systemic antibiotics requires long-term treatment and often fails. We describe a case of a male patient with BLP of the face and scalp, which cultured positive for methicillin-resistant Staphylococcus aureus (MRSA). Subsequent evaluation uncovered a concurrent Treponema pallidum and HIV infections. Treatment of the MRSA with a short course of doxycycline and the syphilis with penicillin, resulted in complete resolution of the skin lesions. Highly Active Anti-Retroviral Therapy for HIV was initiated after the skin lesions had cleared. Resolution of BLP by antibiotic therapy alone in the context of untreated HIV leads the authors to postulate that syphilis may have been the relevant factor contributing to his immune dysregulation.

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Section: Case Reportmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%