With the development of aviation industry, more and more performance requirements are submitted to aero-engines, and structure response and safety problem of aero-engine is concerned. Overview is made of the recently years full engine vibration response due to blade-off. And summary about case containment and rotor dynamic response caused by sudden unbalance in blade-off situation is presented. Then the analysis technologies and modeling methodologies of full engine blade-off structure response are focused. According to the trend, the field of couple vibration analysis should be paid more attention to in the research of full engine dynamic response during blade-off.