Bladder outlet obstruction in painful bladder syndrome/interstitial cystitis

Abstract

Forty-eight percent of our PBS/IC patients have BOO, and increasing severity of PBS/IC is associated with higher voiding pressure.

Clinical symptoms are not reliable in the diagnosis of lower urinary tract dysfunction in women

“…Dysuria was the main symptom in 27.3% of women with bladder oversensitivity, but was only experienced by 2.9% of women with IC/PBS. Although high voiding pressure suggestive of BOO has been noted in patients with IC/PBS, 8 we did not find this phenomenon in this study. The KCl test was reported a reliable modality for differentiating IC/PBS from bladder oversensitivity.…”

Long-term efficacy and tolerability of pentosan polysulphate sodium in the treatment of bladder pain syndrome

“…A similar finding was reported by Cameron and Gajewski in 231 patients with BPS. 25 A possible mechanism of this finding is external sphincter 26 or pelvic floor 27 spasticity due to the pain. The severity of the disease during cystoscopy was another prognostic finding in the study.…”

Risk factors that affect the treatment of interstitial cystitis using intravesical therapy with a dimethyl sulfoxide cocktail

“…Similar results were reported by Cameron et al In their study, 48.1% of 231 women with the NIDDK research definition of IC had evidence of an obstruction on pressure-flow urodynamics. This obstruction was believed to be functional because there was no evidence of urethral stricture disease or other anatomical obstructions noted during cystoscopy or urodynamic catheterization in their patients [28]. However, the etiology of functional obstruction has not been elucidated, but is likely due to pelvic floor muscle spasms secondary to painful voiding.…”