Bladder Diverticulum Simulating a Pelvic Metastasis on a Tc-99m HDP Bone Scan

Abstract

Carcinoma of the prostate was diagnosed in a 74-year-old man. A Tc-99m HDP bone scan was performed as part of the initial staging process. The findings on the bone scan were normal except for an area of increased tracer uptake projected over the left sacroiliac joint, which was seen best on the anterior view. When this was investigated further, the findings of a plain radiograph were inconclusive. Computed tomography showed a large diverticulum projecting from the left side of the bladder; the tracer retained within this diverticulum had produced the findings on the bone scan.

Unsuspected Bladder Diverticulum Resulted in False-Positive 68Ga-DOTATATE Uptake

“…These findings were consistent with bladder diverticulum 4. Bladder diverticulum is common and has been reported in many nuclear medicine studies [5][6][7][8][9]. Most of the case reports occurred in MDP bone scan and FDG PET/CT, whereas such a case observed in the 68 Ga-DOTATATE PET/CT is rare.…”

“…4 Bladder diverticulum is common and has been reported in many nuclear medicine studies. [5][6][7][8][9] Most of the case reports occurred in MDP bone scan and FDG PET/CT, whereas such a case observed in the 68 Ga-DOTATATE PET/CT is rare. Intense DOTATATE uptake in the pelvis can be caused by many different benign or malignant etiologies.…”

99mTc-MDP Uptake in Implantation Metastasis of Gastric Cancer

“…Although bone is generally used to assess osseous lesions, increased extraosseous MDP activity can be seen in numerous etiologies, which can be either benign (4Y7) or malignant (8Y11). Intense activity in the region of the pelvic bone is commonly caused by urinary bladder diverticulum (12,13). Our case indicates that peritoneal seeding from gastric cancer can also result in abnormally increased MDP activity in the pelvis.…”