2019
DOI: 10.1039/c9fo01357a
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Black sea cucumber (Holothuria atraJaeger, 1833) rescuesPseudomonas aeruginosa-infectedCaenorhabditis elegans viareduction of pathogen virulence factors and enhancement of host immunity

Abstract: A strategy to circumvent the problem of multidrug resistant pathogens is the discovery of anti-infectives targeting bacterial virulence or host immunity.

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Cited by 4 publications
(2 citation statements)
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References 57 publications
(68 reference statements)
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“…Methanol extracts of sea cucumber Holothuria atra were reported to inhibit the production of P. aeruginosa virulence factors (elastase, protease, pyocyanin) and restore the expression level of host lys-7 in a Pseudomonas aeruginosainfected Caenorhabditis elegans model (Lee et al, 2019).…”
Section: Sea Cucumber Extractsmentioning
confidence: 99%
“…Methanol extracts of sea cucumber Holothuria atra were reported to inhibit the production of P. aeruginosa virulence factors (elastase, protease, pyocyanin) and restore the expression level of host lys-7 in a Pseudomonas aeruginosainfected Caenorhabditis elegans model (Lee et al, 2019).…”
Section: Sea Cucumber Extractsmentioning
confidence: 99%
“…It is an edible sea cucumber with a rich content of primarily triterpene glycoside saponins (Grauso et al., 2019). H. atra extract demonstrated various biological effects, including antimicrobial, antiproliferative, cytotoxic, antioxidant, and immunostimulatory (Dakrory et al., 2015; Dhinakaran & Lipton, 2014; Lee et al., 2019; Nursid et al., 2021).…”
Section: Introductionmentioning
confidence: 99%