Untitled

Brack, Karin

doi:10.1023/a:1014776425790

Cited by 24 publications

(3 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Lemna polyrhiza was cultured in Hoagland medium in the laboratory for 2 weeks. The Hoagland medium consisted of 0.303 g/l KNO 3 • C.…”

Section: Methodsmentioning

confidence: 99%

“…2 Concentrations of TPT in sediments from four sites in the Götaälv Estuary, Southwest Sweden, ranged from 1.5 to 71 ng/g dry weight (d.w.). 3 Fish (blue gill, largemouth bass and channel catfish) from a pond near a pecan orchard in central Georgia (USA), which had been sprayed with commercial TPT hydroxide mixtures, contained TPT as well as diphenyltin (DPT) and monophenyltin (MPT). 4 TPT and triphenyltin (TBT) are known to be immunotoxic and cause renal and hepatic damage; the relative order of organotin toxicity in astrocyte cultures is TPT > TBT.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Toxic effect of triphenyltin onLemna polyrhiza

Song

Huang

2005

Appl. Organometal. Chem.

View full text Add to dashboard Cite

Little data about toxic effect of triphenyltin (TPT) on aquatic plants is available. The purpose of this paper is to study the toxic effect of TPT on duckweed, Lemna polyrhiza, and the bioconcentration factor of TPT by Lemna polyrhiza. At 5 µg/l concentration TPT treatment, a toxic effect on growth of Lemna polyrhiza appeared. The 8 day IC 50 of TPT to Lemna polyrhiza was 19.22 µg/l. TPT stimulated peroxidase activity and nitrate reductase activity at 2 and 5 µg/l. TPT reduced chloroplast activity of Lemna polyrhiza at 2 and 5 µg/l. Bioconcentration factors of TPT for Lemna polyrhiza were 4.3 and 10.9 at 2 and 5 µg/l, respectively.

show abstract

“…Lemna polyrhiza was cultured in Hoagland medium in the laboratory for 2 weeks. The Hoagland medium consisted of 0.303 g/l KNO 3 • C.…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Toxic effect of triphenyltin onLemna polyrhiza

Song

Huang

2005

Appl. Organometal. Chem.

View full text Add to dashboard Cite

show abstract

“…This area hosts Gothenburg's harbor, the largest harbor in Scandinavia and the biggest oil terminal in Sweden. The contamination in this area is well-documented, including anthropogenic compounds such as organic chlorines, polychlorobiphenyls, petroleum hydrocarbons, polyaromatic hydrocarbons, furans, dioxins, and heavy metals . A method for the assessment of marine pollution should be highly reproducible, easy to use, robust, affordable, and scalable up to automation.…”

Section: Introductionmentioning

confidence: 99%

Proteomics-Based Method for the Assessment of Marine Pollution Using Liquid Chromatography Coupled with Two-Dimensional Electrophoresis

et al. 2007

View full text Add to dashboard Cite

Using a proteomic approach, we have developed a new method for the assessment of marine pollution that generates highly reproducible protein expression patterns and it is simple and scalable. The protocol is based on applying liquid chromatography (LC) coupled with two-dimensional electrophoresis (2-DE) to analyze changes in the protein expression pattern after exposure to marine pollution. The digestive gland of the sentinel "blue mussel" (Mytilus edulis) was batch-processed through a simple cell fractionation followed by ion-exchange chromatography and 2-DE. The selection of ligands, elution method, and small volume design was carefully considered to define a protocol that could be mainly robotized. A pilot study with samples collected from different Gothenburg harbor areas indicated that the clean area could be distinguished from the polluted ones based on a protein expression pattern (PES) composed of 13 proteins. Principal component analysis (PCA) and hierarchical clustering confirmed that the PES was sufficient to discriminate polluted and unpolluted areas and to provide a spatial gradient from the polluted source. Several proteins from the PES were identified by electrospray ionization tandem mass spectrometry (ESI-MS/MS), and they are involved in beta-oxidation, amino acid metabolism, detoxification, protein degradation, organelle biogenesis, and protein folding. In the near future, this methodology could show potential advantages to assess marine pollution and could become a stable platform to elucidate ecotoxicological questions.

show abstract

A gene to organism approach—assessing the impact of environmental pollution in eelpout (Zoarces viviparus) females and larvae

Asker¹,

Almroth²,

Albertsson³

et al. 2015

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

A broad biomarker approach was applied to study the effects of marine pollution along the Swedish west coast using the teleost eelpout (Zoarces viviparus) as the sentinel species. Measurements were performed on different biological levels, from the molecular to the organismal, including measurements of messenger RNA (mRNA), proteins, cellular and tissue changes, and reproductive success. Results revealed that eelpout captured in Stenungsund had significantly higher hepatic ethoxyresorufin O‐deethylase activity, high levels of both cytochrome P4501A and diablo homolog mRNA, and high prevalence of dead larvae and nuclear damage in erythrocytes. Eelpout collected in Göteborg harbor displayed extensive macrovesicular steatosis, whereby the majority of hepatocytes were affected throughout the liver, which could indicate an effect on lipid metabolism. Results also indicate that eelpouts collected at polluted sites might have an affected immune system, with lower mRNA expression of genes involved in the innate immune system and a higher number of lymphocytes. Biomarker assessment also was performed on livers dissected from unborn eelpout larvae collected from the ovary of the females. No significant differences were noted, which might indicate that the larvae to some extent are protected from effects of environmental pollutants. In conclusion, usage of the selected set of biological markers, covering responses from gene to organism, has demonstrated site‐specific biomarker patterns that provided a broad and comprehensive picture of the impact of environmental stressors. Environ Toxicol Chem 2015;34:1511–1523. © 2015 The Authors. Published by SETAC.

show abstract

Untitled

Cited by 24 publications

References 22 publications

Toxic effect of triphenyltin onLemna polyrhiza

Toxic effect of triphenyltin onLemna polyrhiza

Proteomics-Based Method for the Assessment of Marine Pollution Using Liquid Chromatography Coupled with Two-Dimensional Electrophoresis

A gene to organism approach—assessing the impact of environmental pollution in eelpout (Zoarces viviparus) females and larvae

Contact Info

Product

Resources

About