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Kou, Xingming; Meng, Xiang‐Gao; Xie, Juan; Zhang, Xiancheng

doi:10.1023/a:1026078708365

Cited by 24 publications

(15 citation statements)

References 20 publications

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“…This would result in the forming of a hydrated complex in aqueous solution. This hydrated complex may be the real active species [19] for BNPP catalytic hydrolysis. We assume that the mechanism of BNPP catalytic hydrolysis is similar to that of the hydrolytic reaction catalyzed by hydrolytic metalloenzyme.…”

Section: Kinetics Of Bnpp Catalytic Hydrolysismentioning

confidence: 99%

Studies on the reaction kinetics and the mechanism of hydrolysis of bis(4-nitrophenyl)phosphate (BNPP) by hydroxamic acid complexes containing benzo-15-crown-5

Zhou

et al. 2005

Transition Met Chem

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A hydroxamic acid (HL) containing benzo-15-crown-5 and their copper(II), zinc(II), cobalt(II) and manganese(II) complexes have been synthesized and studied as catalysts for the cleavage of bis(4-nitrophenyl)phosphate (BNPP). The catalytic properties of these complexes and the kinetics and mechanism of BNPP hydrolysis have been investigated. The kinetic mathematical model of BNPP cleavage catalyzed by these complexes has been proposed. The effects of reaction temperature and metal ion in the complexes on the rate of BNPP catalytic hydrolysis have been discussed. The results show that the hydroxamic acid complexes containing benzo-15-crown-5 exhibit high activity in the BNPP catalyzed hydrolysis; the pseudo-first-order-rate constants of BNPP hydrolysis catalyzed by the complexes increase along with the increases of pH of the buffer solution from 7.50 to 9.50; the activity of different metal ions decreases in the order: Co 2+ > Cu 2+ > Zn 2+ > Mn 2+ ; the pseudo-first-order-rate constants of BNPP hydrolysis catalyzed by the complexes is 2.24 · 10 5 $ 3.24 · 10 5 times as large as that of spontaneous hydrolysis of BNPP.

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Section: Kinetics Of Bnpp Catalytic Hydrolysismentioning

confidence: 99%

Studies on the reaction kinetics and the mechanism of hydrolysis of bis(4-nitrophenyl)phosphate (BNPP) by hydroxamic acid complexes containing benzo-15-crown-5

Zhou

et al. 2005

Transition Met Chem

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show abstract

“…This would result in the forming of a hydrated complex in aqueous solution. This hydrated complex may be the real active species [23] for the PNPP catalytic hydrolysis. We assume that the mechanism of PNPP catalytic hydrolysis is similar to that of the hydrolytic reaction catalyzed by hydrolytic metalloenzyme.…”

Section: Kinetics Of Pnpp Catalytic Hydrolysismentioning

confidence: 99%

PNPP catalytic hydrolysis by mono- and binuclear transition-metal complexes with polyether-bridged dihydroxamic acids

Xie

et al. 2004

Transition Met Chem

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Polyether-bridged dihydroxamic acids and their mono-and binuclear copper(II), and cobalt(II) complexes have been synthesized and employed as models to mimic hydrolase in the catalytic hydrolysis of p-nitrophenyl picolinate (PNPP). The kinetics and the mechanism of PNPP hydrolysis have been investigated. The kinetic mathematical model of PNPP cleavage by the complexes has been proposed. The effects of the different central metal ion, monoand binuclear metal, the pseudo-macrocyclic polyether constructed by the polyethoxy group in complexes, and reactive temperature on the rate of PNPP catalytic hydrolysis have been examined. The results show that the transition-metal dihydroxamates exhibit high catalytic activity in the PNPP hydrolysis; the rate of the PNPP hydrolysis increases with the increase in pH of the buffer solution; the catalytic activity of binuclear complexes is higher than that of mononuclear complexes; the catalytic activity of copper(II) complex is about four times that of the cobalt(II) complex; the pseudo-macrocyclic polyether can synergetically activate H 2 O coordinated to the metal ion with the central metal ion together and promote the PNPP catalytic hydrolysis.

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“…A large number of studies on mimics for hydrolytic metalloenzymes have used Schiff base complexes. [8][9][10] Among them, the crown ether-containing Schiff bases have attracted much attention because crown rings could endow functional molecules with novel performance and character owing to the hydrophobicity of the outer ethylene groups and orderly arrangement of inner oxygen atoms. 11,12 Previously, the catalytic performances of monoSchiff base complexes with aza-crown ether or morpholino pendants in p-nitrophenyl picolinate (PNPP) hydrolysis have been reported.…”

Section: Introductionmentioning

confidence: 99%

p‐Nitrophenyl Picolinate Cleavage by Unsymmetrical Bis‐Schiff Base Manganese(III) and Cobalt(II) Complexes with Aza‐Crown Ether or Morpholino Pendants

Wang

et al. 2011

Chin. J. Chem.

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The unsymmetrical bis-Schiff base manganese(III) and cobalt(II) complexes with either benzo-10-aza-crown ether pendants (MnL 1 Cl, MnL 2 Cl) or morpholino pendant (MnL 3 Cl, CoL 3 ) have been employed as models for hydrolase by studying the kinetics of their hydrolysis reactions with p-nitrophenyl picolinate (PNPP). A kinetic model of PNPP cleavage catalyzed by these complexes is proposed. The effects of complex structures and reaction temperature on the rate of PNPP hydrolysis have been examined. All four complexes exhibit high catalytic activity and the rate increases with pH under 25 ℃. The complexes of ligands containing a crown ether group exhibit higher catalytic activities than the non-crown analogues. The catalytic activity of the complexes follows the order Mn(III)＞Co(II) under the same ligands.

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Untitled

Cited by 24 publications

References 20 publications

Studies on the reaction kinetics and the mechanism of hydrolysis of bis(4-nitrophenyl)phosphate (BNPP) by hydroxamic acid complexes containing benzo-15-crown-5

Studies on the reaction kinetics and the mechanism of hydrolysis of bis(4-nitrophenyl)phosphate (BNPP) by hydroxamic acid complexes containing benzo-15-crown-5

PNPP catalytic hydrolysis by mono- and binuclear transition-metal complexes with polyether-bridged dihydroxamic acids

p‐Nitrophenyl Picolinate Cleavage by Unsymmetrical Bis‐Schiff Base Manganese(III) and Cobalt(II) Complexes with Aza‐Crown Ether or Morpholino Pendants

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