Bizarre leiomyoma of the scrotum: A case report and review of the literature

Su, Zhengming; Li, Ganhong; Wang, Yadong; Yu, Zuhu; Chen, Zebo; Ni, Liangchao; Yang, Shangqi; Ye, Jiongxian; Lai, Yongqing

doi:10.3892/ol.2014.1930

Cited by 5 publications

(3 citation statements)

References 8 publications

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“…In the male genital tract, these tumours are considered exceedingly rare, and most cases have been published in the form of case reports. In this population, leiomyoma with bizarre nuclei has a predilection for the fourth to seventh decade of life 5. No difference in incidence has been demonstrated between the right and the left testicle and they can present either as a bilateral lesion or as a unilateral lesion, with the latter occurring in more than 80% of cases 6.…”

Section: Introductionmentioning

confidence: 95%

Leiomyoma with bizarre nuclei of the scrotum: a rare entity

et al. 2022

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Leiomyomas of the paratesticular region are a rare entity. A subtype of leiomyomas called bizarre nuclei leiomyoma is even rarer and histologically present some interesting features that are important to recognise to make the differential diagnosis with its malignant counterpart—leiomyosarcoma. We present a case of a man in his 60s, who presented with a painless mass on the right testicle. The clinical diagnosis was of an epidermoid cyst. The mass was excised and a diagnosis of leiomyoma of bizarre nuclei was made.

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Section: Introductionmentioning

confidence: 95%

Leiomyoma with bizarre nuclei of the scrotum: a rare entity

et al. 2022

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“…While leiomyomas are typically painless, they can be associated with pain and the development of hydroceles [5].…”

Section: Introductionmentioning

confidence: 99%

Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case Report

Sana Ahuja,

Verma,

Aziz Khan

et al. 2024

ann urol oncol

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Leiomyomas, originating from smooth muscle cells, are common in the uterus but rare in the scrotum, presenting a clinical challenge. Scrotal leiomyomas, first described in the 19th century, are characterized by benign pathology from the subcutaneous dartos muscle. We present two cases of middle-aged males with scrotal leiomyomas, detailing clinical presentations, histopathological findings, and immunohistochemistry results. The first involved a 48-year-old with a painless scrotal lump, excised to reveal well-circumscribed smooth muscle bundles. Immunohistochemistry confirmed vimentin, desmin, and smooth muscle actin (SMA) positivity, consistent with scrotal leiomyoma. The second case featured a 25-year-old with a painless scrotal swelling, histologically matching the features of scrotal leiomyoma. Accurate diagnosis is crucial for guiding appropriate management strategies. Clinicians often employ a combination of clinical evaluation, imaging studies, and histopathological examination to confirm the presence of scrotal leiomyomas. Ultrasound remains a valuable tool for assessing the size, location, and vascularity of the tumor, aiding in the formulation of a differential diagnosis. Definitive diagnosis, however, relies on histological examination, which typically reveals spindle-shaped smooth muscle cells arranged in interlacing bundles.

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“…Leiomyoma with bizarre nuclei (LBN) is an infrequent variant of uterine smooth muscle neoplasm. 1,2 Although LBN is most commonly defined in the uterus, it has been reported in the literature that to also seen in localizations, such as the vagina, 3 scrotum, 4 renal pelvis, 5 and prostate gland. 6 Herein, we present a very rare case of LBN localized in the paratubal cyst wall.…”

Section: Introductionmentioning

confidence: 99%

Leiomyoma with Bizarre Nuclei (Symplastic Leiomyoma) in the Paratubal Cyst Wall: Report of a Rare Case

Çelik

2021

Int J Surg Pathol

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Leiomyoma is a benign mesenchymal tumor that develops from smooth muscle cells. It can present in various histological variants. Leiomyoma with bizarre nuclei is an infrequent variant of uterine smooth muscle neoplasm. It is characterized by focally or diffusely distributed bizarre cells on the background of a typical leiomyoma. These bizarre cells are large, multinucleated, or multilobulated and have an eosinophilic cytoplasm. Even though leiomyomas with bizarre nuclei display benign clinical behavior, their differential diagnosis from leiomyosarcoma can sometimes be difficult. Leiomyoma has been described most commonly in the uterus. There is no case of leiomyoma originating from paratubal cysts described in the literature. In this article, we present a rare case of leiomyoma with bizarre nuclei originating from a paratubal cyst.

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Bizarre leiomyoma of the scrotum: A case report and review of the literature

Cited by 5 publications

References 8 publications

Leiomyoma with bizarre nuclei of the scrotum: a rare entity

Leiomyoma with bizarre nuclei of the scrotum: a rare entity

Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case Report

Leiomyoma with Bizarre Nuclei (Symplastic Leiomyoma) in the Paratubal Cyst Wall: Report of a Rare Case

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