Bisphenol A and thyroid hormones

Abstract

Bisphenol A (BPA) is a well-known endocrine-disrupting chemical which can cause potential health risks and interfere with thyroid hormones through multiple avenues. This study aimed to evaluate the hotspots and emerging trends on BPA and thyroid hormones by using a bibliometric method. Publications related on BPA and thyroid hormones were downloaded from Science Citation Index-Expanded database. Annual outputs, high yield journals, countries, institutions, authors and their cited times were summarized. In addition, keywords co-occurrence, burst references and citation networks were bibliometric analyzed. From 2000 to 2019, 418 articles were published. Both of the Environment International and Environmental Health Perspectives , United States, Chinese Academy of Sciences and Antonia M. Calafat were the most recorded journals, countries, institutions and authors, respectively. The main research area was Toxicology. In addition of the retrieve term “bisphenol-a” and “thyroid-hormone”, “in-vitro”, “exposure” and “endocrine disruptors”, were the hotspot keywords and “triclosan”, “oxidative stress” and “united-states” were the most recent trends keywords. “Thyroid hormone action is disrupted by Bisphenol A as an antagonist” published on The Journal of Clinical Endocrinology & Metabolism by Kenji Moriyama in 2002 got both the highest burst score and citation score. Six groups were clustered and the mechanism of BPA's effect on thyroid hormones, and the exposure of BPA and potential risks in children and pregnant women were the two main large fields. The number of publications in the field of BPA and thyroid hormones has increased tremendously since 2000. The research hotspot ranged from mechanism researches in animal models to epidemiological studies. “Thyroid hormone action is disrupted by bisphenol A as an antagonist” of Kenji Moriyama provided important building blocks in the field. The impact of BPA on thyroid hormones, especially pregnant women and children, was the latest research frontiers and might be the future direction of this filed in the following years.

Relationship of urinary bisphenol A in childhood on thyroid hormone function in adolescents: a cohort study

“…There are several limitations to our study. First, BPA exposure was measured with a single spot urine sample, which may not represent the average long-term exposure due to short half-life and body variability of bisphenols [11,25]. Second, this study included a limited number of bisphenols.…”

The impact of heat on kidney health: A PRISMA-compliant bibliometric analysis

“…The methodology adopted in this study followed the principles of bibliometric analysis applied in similar published bibliometric studies. [23][24][25] This method used a set of quantitative descriptive techniques for the analysis of scientific information, which was regrouped into 2 main categories: performance analysis and science mapping. The analysis was supported by 3 enrichment techniques: networking, clustering, and visualization.…”

Iodine as a potential endocrine disruptor—a role of oxidative stress

“…Regarding the effects of bisphenol A on the thyroid gland, numerous studies (experimental, clinical observational, and epidemiological) were performed and related papers have been published; they were recently summarized in bibliometric analysis [40]. Generally, it can be stated that bisphenol A disrupts or antagonizes thyroid function [40], which is in agreement with the inverse association between the level of this EDC and thyroid hormone concentrations [41,42]. Interestingly, a positive association was found between bisphenol A and occurrence of thyroid nodules in women with positive thyroid antibodies [43], which could also result from diminished thyroid function.…”