Bisphenol A and other compounds in human saliva and urine associated with the placement of composite restorations

Kingman, Albert; Hyman, Jeffrey; Masten, Scott A.; Jayaram, Beby; Smith, Cynthia R.; Eichmiller, Frederick; Arnold, Michael C.; Wong, Paul A.; Schaeffer, James M.; Solanki, Sheetal; Dunn, William J.

doi:10.14219/jada.archive.2012.0090

“…As the release was measured to be spread over 3 days, the short-term exposure would be between 0.43 and 4.43 μg/kg bw/day. These in vitro data could not be confirmed by other groups, but small amounts of BPA released from dental resins were found immediately and within a day or two after placement (e.g., [2,8]). The question remains, which impact these data have for the patient, the dental personnel and the environment.…”

contrasting

confidence: 60%

BPA from dental resin material: where are we going with restorative and preventive dental biomaterials?

Goldberg

¹

,

Dimitrova-Nakov

²

,

Schmalz

³

2014

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…In clinical dentistry, BPA is a precursor of the bisphenol A glycidyl methacrylate (Bis-GMA), bisphenol A dimethacrylate (Bis-DMA), and bisphenol A ethoxylated dimethacrylate (Bis-EMA) monomers found in dental sealants, adhesive resins, 2 and composite resins. The degradation of these materials can leach BPA [3][4][5][6] into the oral environment, which could be a clinical concern and could be exacerbated by temperature changes, mechanical wear, 7 changes in pH, 8 and bacterial or salivary enzymatic action.…”

Section: Introductionmentioning

confidence: 99%

An investigation into bisphenol-A leaching from orthodontic materials

Kotyk¹,

Wiltshire

²

2014

The Angle Orthodontist

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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“…So, residual BPA, not chemically converted into bis-GMA, is likely present in trace amounts in any dental material containing these ingredients of dental composites and sealants degrading in the oral cavity by the action of salivary enzymes [30]. Thus, dental treatment with composite restorations could be a possible source of exposure to BPA for each individual being currently or potentially dental patient [31] as well as for occupationally exposed dental professionals and for dental students during their educational course.…”

Section: Discussionmentioning

confidence: 99%

Pilot study of contact sensitization to rubber allergens and bisphenol A amongst dental students

Lyapina

¹

,

Krasteva

²

,

Dencheva

³

et al. 2017

Int J Occup Med Environ Health

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

show abstract

Bisphenol A and other compounds in human saliva and urine associated with the placement of composite restorations

Cited by 111 publications

References 19 publications

BPA from dental resin material: where are we going with restorative and preventive dental biomaterials?

BPA from dental resin material: where are we going with restorative and preventive dental biomaterials?

An investigation into bisphenol-A leaching from orthodontic materials

Pilot study of contact sensitization to rubber allergens and bisphenol A amongst dental students

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