Bisphenol A Analog-Imprinted Polymers Prepared by an Immobilized Template on a Modified Silica Microsphere Matrix

Binding behaviour of molecularly imprinted polymers prepared by a hierarchical approach in mesoporous silica beads of varying porosity

“…The main advantage of such an approach consists of the easy preparation of spherical imprinted polymeric particles of narrow diameter and pore size distribution, particularly indicated for chromatographic applications. The validity of this approach was further demonstrated for imprinted beads with molecular recognition properties towards 9-ethyladenine and triaminopyrimidine [6], the protected dipeptide FMOC-PheGly-OH [7,8] and bisphenol A [9]. In a simpler approach, isoproterenol-imprinted beads were prepared by filling pores of butyl-capped silica beads with a polymerization mixture containing the template, thus eliminating the need for the covalent immobilization of the template on the surface of the silica pores [10].…”

Molecularly Imprinted Tailor-Made Functional Polymer Receptors for Highly Sensitive and Selective Separation and Detection of Target Molecules

“…After the formation of the polymer matrix in the pores of the silica beads, an NH4HF2 treatment was conducted to dissolve the silica matrix. Spherical MIP beads for BPA recognition were obtained as a result [33].…”

“…4-VPy was used as a functional monomer capable of hydrogen bonding and π-π stacking in molecular imprinting for non-steroidal anti-inflammatory drug piroxicam [43], BPA [33], and sialic acid [44]. Since 4-VPy works as a ligand for metal ions, a diketon compound, dibenzoylmethane, was molecularly imprinted using a Co(II) complex of one dibenzoylmethane and two 4-VPy, where the formation of binding sites was controlled by metal ion coordination [45].…”

Monodispersed, molecularly imprinted polymers as affinity-based chromatography media

“…Similarly, MIPs for l-isoproterenol [89], 9-ethyladenine and triaminopyrimidine [90], dipeptide [91,92] and BPA [93] were prepared. The prepared MIP for 9-fluorenylmethyloxycarbonyl (FMOC)-Phe-OH, preferentially retained N-protected Phe derivatives, including the dipeptide FMOC-Phe-Gly-OH, with ca.…”