Bispecific Antibodies Produced via Chemical Site-Specific Conjugation Technology: AJICAP Second Generation
Tomohiro Fujii,
Kenichiro Ito,
Kazutoshi Takahashi
et al.
Abstract:Bispecific antibodies are biotherapeutics that amalgamate the specificities of two distinct antibodies into one molecule. Bispecific antibodies can be utilized in a broad range of diagnostic and therapeutic applications; however, their engineering requires genetic modification and remains time-consuming. Therefore, in this study, we used AJICAP second-generation technology, which drives the production of site-specific antibody-drug conjugates in a practical and robust manner, without genetic modification requi… Show more
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