Bisoprolol: A comprehensive profile

Bakheit, Ahmed H.; Ali, Raisuddin; Alshahrani, Ali D; El‐Azab, Adel S.

doi:10.1016/bs.podrm.2020.07.006

Cited by 6 publications

(6 citation statements)

References 40 publications

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“…SWV has a higher sensitivity than a differential pulse that does not involve reverse current. It has lower detection limits of up to 10 ‐9 M. [ 35,36 ]…”

Section: Resultsmentioning

confidence: 99%

“…SWV has a higher sensitivity than a differential pulse that does not involve reverse current. It has lower detection limits of up to 10 -9 M. [35,36] Thus, the SW voltammograms of 26.0×10 -9 mol L -1 sufentanil at the surface of MMIP-CP, MNIP-CP, and bare CP electrodes were recorded. The results are presented in figure 5.…”

Section: Electrochemical Behavior Of Sufentanil and Washing Effectsmentioning

confidence: 99%

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Magnetic molecularly imprinted polymer for trace pharmaceutical analysis: Preconcentration and the electrochemical determination of sufentanil in biological fluids

Abedi,

Roostaie

2023

Vietnam Journal of Chemistry

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A magnetic molecularly imprinted electrochemical sensor was developed for selective determination of sufentanil (SUF) based on carbon paste electrode (CPE) modified with methacrylic acid‐ethylene glycol dimethacrylate‐coated Fe3O4 nanoparticles (Fe3O4@MAA‐EGDMA NPs). The structural properties, chemical structure, and electrochemical behaviors of the imprinted sensor were characterized by X‐ray diffraction analysis (XRD), Fourier transform infrared spectroscopy (FT‐IR), and square wave voltammetry (SWV), respectively. The prepared sensor revealed admirable recognition ability and selectivity for sufentanil. The substantial variables affecting the performance of extraction and SWV were considered and optimized by the batch mode experiment. Under optimal conditions, the method was capable of determining SUF in the range of 1.0×10‐9 to 6.0×10‐8 mol L‐1. The limit of detection (LOD) of sufentanil was found to be 0.2×10‐9 mol L‐1 (n = 10). The accuracy of the method was studied by recovery measurements on spiked samples. Admirable recovery results (96.0‐102.5%) with satisfactory relative standard deviation (RSD) were attained. According to the obtained results, the present method has high selectivity and reliability for the preconcentration and determination of sufentanil in various biological samples, including urine and plasma, without the use of sample pretreatments.

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“…SWV has a higher sensitivity than a differential pulse that does not involve reverse current. It has lower detection limits of up to 10 ‐9 M. [ 35,36 ]…”

Section: Resultsmentioning

confidence: 99%

Section: Electrochemical Behavior Of Sufentanil and Washing Effectsmentioning

confidence: 99%

Magnetic molecularly imprinted polymer for trace pharmaceutical analysis: Preconcentration and the electrochemical determination of sufentanil in biological fluids

Abedi,

Roostaie

2023

Vietnam Journal of Chemistry

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“…It is mainly eliminated via renal excretion in unchanged form, and less than 10% undergone hepatic metabolism by CYP3A4. While absorption and clearance of bisoprolol is closely related to OATP1A2 and P-glycoprotein [48].…”

Section: Manuscriptmentioning

confidence: 99%

An Update on Impacts of Epigallocatechin Gallate Co-administration in Modulating Pharmacokinetics of Statins, Calcium Channel Blockers, and Beta-blockers

et al. 2023

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Brewed green tea, green tea extract (GTE), and its primary active compound, epigallocatechin gallate (EGCG) may interact with drugs and alter the drug’s therapeutic effectiveness ultimately leading to therapeutic failure or drug overdose. Several isolated reports have claimed that EGCG is the main active ingredient that causes these effects. Several isolated reports have claimed that EGCG is the main active ingredient that causes these effects. While a few studies aimed to uncover evidence of EGCG-drug interactions, no study has thoroughly and collectively reviewed them. EGCG is a potential cardio-protective agent used by many patients with cardiovascular diseases as a complementary medicine alongside conventional modern medications, either with or without the knowledge of their physicians. Therefore, this review focuses on the impact of concurrent EGCG supplementation on pharmacokinetics and pharmacodynamics of several commonly used cardiovascular drugs (statins, beta-blockers, and calcium channel blockers). Pubmed index was searched for keywords related to this review, without year limit and the results analysed for interactions of cardiovascular drugs with EGCG. This review concludes that EGCG increases systemic circulation of several statins (simvastatin, fluvastatin, rosuvastatin,) and calcium channel blockers (verapamil), but decreases the bioavailability of beta-blockers (nadolol, atenolol, bisoprolol). Further studies on its clinical significance in affecting drug efficacy are required.

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“…Chemically, bisoprolol is 1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy] propan-2-ol and its common form in the solid pharmaceutical dosage forms is bisoprolol fumarate, which is very soluble in water. 1 Its wide use implies the need for efficient and reliable analytical methods for its quality control, including methods for characterization of its related substances.…”

Section: Introductionmentioning

confidence: 99%

Forced degradation studies and structural characterization of related substances of bisoprolol fumarate in finished drug product using LC-UV-MS/MS

Lazarevska-Todevska

Piponski²,

Стефова

2022

JSCS

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Methods for determination of bisoprolol and related substances mostly use UV detection and phosphate buffer and are not suitable for MS detection. In this study, LC-UV-MS/MS for separation and characterization of bisoprolol related substances was developed, validated, and applied for studying the degradation products of bisoprolol when exposed to hydrolytic stress, heat and light. The method uses C18 column, formic acid in water and acetonitrile as mobile phases, gradient elution, UV, and MS detection. Forced degradation revealed that acid hydrolysis produces the most intensive transformation of bisoprolol to its impurity A, along with impurities L and D. Alkaline hydrolysis produced impurities A, L, Q, G, and K; oxidative and thermal degradation produced impurities A, L, and K, and photodegradation produced impurities A, L, G and, K, all characterized by their mass spectral data. The developed method using two detection systems was demonstrated as efficient since mass spectra allowed identification of the related substances of bisoprolol and quantification was possible using absorbance measurement at 270 nm. The obtained results will fill in the lack of data on the fragmentation patterns of bisoprolol and related substances that can be used by researchers and practitioners in research and quality control laboratories.

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Bisoprolol: A comprehensive profile

Cited by 6 publications

References 40 publications

Magnetic molecularly imprinted polymer for trace pharmaceutical analysis: Preconcentration and the electrochemical determination of sufentanil in biological fluids

Magnetic molecularly imprinted polymer for trace pharmaceutical analysis: Preconcentration and the electrochemical determination of sufentanil in biological fluids

An Update on Impacts of Epigallocatechin Gallate Co-administration in Modulating Pharmacokinetics of Statins, Calcium Channel Blockers, and Beta-blockers

Forced degradation studies and structural characterization of related substances of bisoprolol fumarate in finished drug product using LC-UV-MS/MS

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