Bisabolane sesquiterpene and cyclopentene derivatives from the marine algal-derived endophytic fungus Trichoderma asperellum EN-764

Li, Hong-Lei; Li, Xiaoming; Ying, Zhen; Li, Yanhe; Wang, Bin‐Gui

doi:10.1016/j.phytochem.2023.113644

Cited by 5 publications

(2 citation statements)

References 27 publications

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“…The relative configuration of 1 was elucidated by analysis of NOESY data ( Figure 3 ). In the NOESY spectrum, there was NOE correlation between H-5 and Me-10, which suggested the anti relationship between H-5 and H-8 [ 22 , 23 ]. Therefore, the relative configuration of 1 was determined to be 5 R *, 8 R *.…”

Section: Resultsmentioning

confidence: 99%

Four Undescribed Pyranones from the Scutellaria formosana-Derived Endophytic Fungi Ascomycota sp. FAE17

Yang

Chen

et al. 2023

Molecules

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Four undescribed pyranone derivatives, named ascomycopyrones A–D (1–4), as well as one known analogue simplicilopyrone (5) (this is the first study to report the absolute configuration), were isolated from the endophytic fungus Ascomycota sp. FAE17 derived from the flowers of Scutellaria formosa. The structures of these pyranones were identified by comprehensive spectroscopic and MS analyses, and the absolute configurations were determined by their experimental and quantum chemical electronic circular dichroism (ECD) calculations. All isolated compounds were tested for various bioactivities, including antibacterial, cytotoxic activity, and NO inhibitory activity. Unfortunately, none of the compounds showed significant bioactivities.

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Section: Resultsmentioning

confidence: 99%

Four Undescribed Pyranones from the Scutellaria formosana-Derived Endophytic Fungi Ascomycota sp. FAE17

Yang

Chen

et al. 2023

Molecules

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“…cucumerinum . During our search for biocontrol agents for use in agriculture, − a cold-seep-sediment-derived fungus of Pseudallescheria boydii CS-793 attracted our attention because of its inhibitory effect on Fusarium proliferatum (Figure S110). The search for its antagonistic metabolites resulted in the discovery of 10 novel bergamotene-derived sesquiterpenoids ( 1 – 10 ) (Figure ).…”

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confidence: 99%

Antifungal Pseuboyenes A–J, Bergamotene-Derived Sesquiterpenoids from a Cold-Seep-Derived Pseudallescheria boydii

Ying,

Li,

Yang

et al. 2024

J. Nat. Prod.

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A chemical investigation of a cold-seep-sedimentderived fungus, Pseudallescheria boydii CS-793, resulted in characterization of 10 novel bergamotene-derived sesquiterpenoids, pseuboyenes A−J (1−10). Their structures were elucidated by spectroscopic and X-ray crystallographic analyses as well as using the modified Mosher's method. Compound 1 represents the first example of a β-bergamotene containing a 6-oxobicyclo[3.2.1]octane nucleus adducted with a methyl lactate unit, while 8−10 involve a skeletal rearrangement from bergamotene. Compounds 2−5 showed significant antifungal activities against Colletotrichum gloeosporioides Penz. and Fusarium oxysporum with MICs ranging from 0.5 to 8 μg/mL. Compound 4 exhibited an in vitro anti-F. proliferatum effect with an EC 50 value of 1.0 μg/mL.

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Exploration of diverse secondary metabolites from Penicillium brasilianum by co-culturing with Armillaria mellea

Rong,

Zhang,

et al. 2024

Appl Microbiol Biotechnol

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Bisabolane sesquiterpene and cyclopentene derivatives from the marine algal-derived endophytic fungus Trichoderma asperellum EN-764

Cited by 5 publications

References 27 publications

Four Undescribed Pyranones from the Scutellaria formosana-Derived Endophytic Fungi Ascomycota sp. FAE17

Four Undescribed Pyranones from the Scutellaria formosana-Derived Endophytic Fungi Ascomycota sp. FAE17

Antifungal Pseuboyenes A–J, Bergamotene-Derived Sesquiterpenoids from a Cold-Seep-Derived Pseudallescheria boydii

Exploration of diverse secondary metabolites from Penicillium brasilianum by co-culturing with Armillaria mellea

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