Bis(oxotremorine) fumarate bis(fumaric acid)

Abstract

The title compound, bis(oxotremorine) fumarate bis(fumaric acid) {systematic name: 1-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]pyrrolidinium (2E)-but-2-enedioate bis[(2E)-but-2-enedioic acid]}, 2C12H19N2O+·C4H2O4 2−·2C4H4O4, has a single oxotremorine monocation protonated at the pyrrolidine nitrogen, one fumaric acid molecule and half of a fumarate dianion in the asymmetric unit. The ions and fumaric acid molecules are held together by N—H...O and O–H-...O hydrogen bonds in 40-membered rings with graph-set notation R 6 6(40). The fumarate ions join these rings into infinite chains along [001].

N-Cyclohexyltryptamine: freebase, bromide and fumarate

“…This includes the zwitterionic natural product baeocystin (Naeem, Sherwood et al, 2022), its metabolite norpsilocin as both its freebase and fumarate (Chadeayne et al, 2020b), and its synthetic prodrug 4-acetoxy-N-methyltryptamine as a chloride salt (Glatfelter et al, 2022b). The remaining three are N-methylserotonin hydrogen oxalate (Naeem, Anas et al, 2023), 4-benzyloxy-N-isopropyltryptammonium chloride and 4-hydroxy-N-isopropyltryptamine (Laban et al, 2023) There are only four structures of freebase tryptamines known without indole substitution: the natural products tryptamine (Nowell et al, 2002) and N,N-dimethyltryptamine (Falkenberg, 1972), as well as N-methyl-N-propyltryptamine (Chadeayne et al, 2019b), and 3-[2-(piperidin-1-yl)ethyl]-1Hindole (Sahoo et al, 2020), while many other tryptamine freebases have been reported including serotonin .…”