Bis[3-(2H-benzotriazol-2-yl)-2-(prop-2-ynyloxy)-5-(2,4,4-trimethylpentan-2-yl)phenyl]methane

Abstract

In the title compound, C47H54N6O2, the C—C—C bond angle between the rings is 108.40 (13)°. One aryl ring aligned at 38.5 (1)° with respect to the N-heterocyclic substituent and the other at 56.0 (1)° with respect to its substituent. In the crystal, adjacent mol­ecules are linked by C—H⋯N hydrogen bonds, forming a chain extending along the a axis.

Synthesis, biological evaluation and in silico investigations of benzotriazole derivatives as potential inhibitors of NIMA related kinase

“…The results show that the molecules interact through hydrogen bonds as C–H⋯N, and are responsible for the building of an extended chain parallel to the axis. 58 Hence all the afforded results confirm the synthesis of compound (3).…”