Bis(2-ethylhexyl)-tetrabromophthalate Poses a Higher Exposure Risk and Induces Gender-Specific Metabolic Disruptions in Zebrafish Liver
Kaiyu Fu,
Biran Zhu,
Yumiao Sun
et al.
Abstract:Bis(2-ethylhexyl)-tetrabromophthalate (TBPH), a typical
novel brominated
flame retardant, has been ubiquitously identified in various environmental
and biotic media. Consequently, there is an urgent need for precise
risk assessment based on a comprehensive understanding of internal
exposure and the corresponding toxic effects on specific tissues.
In this study, we first investigated the toxicokinetic characteristics
of TBPH in different tissues using the classical pseudo-first-order
toxicokinetic model. We fou… Show more
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