Birth weight and gestational age in newborns exposed to maternal obsessive-compulsive disorder

Uğuz, Faruk; Yüksel, Gökşen; Karşıdağ, Çağatay; Guncu, Hatice; Konak, Murat

doi:10.1016/j.psychres.2014.12.063

Cited by 16 publications

(9 citation statements)

References 18 publications

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“…Elevation of OC symptoms in pregnant women during the COVID-19 pandemic carries serious public health implications. OCD during pregnancy is associated with adverse obstetric outcomes including lower birth weight and younger gestational age at birth (Uguz et al 2015 ). Perinatal anxiety disorders, such as OCD, are also associated with reduced parental self-efficacy, poorer maternal quality of life (Challacombe et al 2016 ; Gezginç et al 2008 ), and infant attachment problems (Challacombe et al 2016 ; Miller & O’Hara 2020 ).…”

Section: Discussionmentioning

confidence: 99%

Elevated risk for obsessive–compulsive symptoms in women pregnant during the COVID-19 pandemic

Mahaffey

Levinson

Preis

et al. 2021

Arch Womens Ment Health

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The COVID-19 pandemic has led to a public mental health crisis with many people experiencing new or worsening anxiety. Fear of contagion and the lack of predictability/control in daily life increased the risk for problems such as obsessive-compulsive disorder (OCD) in the general population. Pregnant women may be particularly vulnerable to such pandemic-related stressors yet the prevalence of OC symptoms in this population during the pandemic remains unknown. We examined the prevalence of OC symptoms in a sample of 4451 pregnant women in the USA, recruited via targeted online methods at the start of the pandemic. Participants completed self-report measures including the Obsessive-Compulsive Inventory-Revised and the Pandemic-Related Pregnancy Stress Scale. Clinically significant OC symptoms were present in 7.12% of participants, more than twice as high as rates of peripartum OCD reported prior to the pandemic. Younger maternal age, income loss, and suspected SARS-CoV-2 infection were all associated with higher OC symptoms. Two types of pregnancy-specific stress, pandemic-related and pandemic-unrelated, were both associated with higher levels of OC symptoms. Pandemicrelated pregnancy stress predicted OC symptoms even after controlling for non-pandemic-related, pregnancy-specific stress. Elevated rates of OC symptoms were observed in women pregnant during the pandemic, particularly those experiencing elevated pandemic-related pregnancy stress. This type of stress confers a distinct risk for OC symptoms above and beyond pregnancy-specific stress and demographic factors. Healthcare providers should be prepared to see and treat more peripartum women with OC symptoms during this and future public health crises.

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Section: Discussionmentioning

confidence: 99%

Elevated risk for obsessive–compulsive symptoms in women pregnant during the COVID-19 pandemic

Mahaffey

Levinson

Preis

et al. 2021

Arch Womens Ment Health

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“…However, the relationship between OCD and neonatal outcome in particular has received little rigorous examination. In a recent study, Uguz et al (2015) reported a significant difference between birth weight and gestational age at delivery, with the infants of mothers with OCD being smaller and having shorter gestations compared to infants of mothers without OCD; however, this study was relatively small, including only 28 cases of OCD (Uguz 2015). Additionally, parental OCD has been associated with increased risk of an anxiety disorder in the offspring (Black et al 2003).…”

Section: Introductionmentioning

confidence: 61%

Obsessive-compulsive disorder in pregnancy and the postpartum period: course of illness and obstetrical outcome

House

Tripathi

Knight

et al. 2015

Arch Womens Ment Health

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Purpose To examine the course of obsessive-compulsive disorder (OCD) across pregnancy and its impact on obstetric and neonatal outcomes. Methods Women enrolled prior to 20 weeks gestation in a prospective, observational study. The Structured Clinical Interview for DSM-IV was completed to obtain lifetime Axis I diagnoses. A total of 56 women with OCD were followed at 1 to 3 month intervals through 52 weeks postpartum. Each visit, the Yale-Brown Obsessive Compulsive Scale (YBOCS), clinical assessment, and medication/exposure tracking was performed. Obstetric and neonatal data was abstracted from the medical record. In subjects with OCD, associations between perinatal obsessive-compulsive symptoms (OCS) and outcomes were examined. Additionally, outcomes were compared to 156 matched psychiatric patients without OCD. Results Maternal age inversely correlated with the YBOCS scores across the study period (β = -0.5161, p = .0378). Caesarean section was associated with increased OCS in the postpartum period compared to vaginal delivery (β = 5.3632, p = 0.043). No associations were found between severity of perinatal obsessions or compulsions with any specific obstetric or neonatal complications. Subjects without OCD had higher frequency of fetal loss compared to mothers with OCD (χ² = 4.03, p = 0.043). Conclusions These novel prospective data fail to identify an association of OCS with adverse outcomes. In contrast, there is an association of delivery method and younger maternal age with increased postnatal symptoms of OCD. Psychiatric subjects without OCD may have a higher risk of miscarriage and intrauterine fetal demise compared to subjects with OCD.

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“…Disorder on Pregnancy and Outcomes Uguz et al (2015) examined the impact of OCD during pregnancy on gestational age and birthweight of the infants. The sample consisted of 28 women with OCD and 35 women without OCD.…”

Section: Impact Of Obsessive-compulsivementioning

confidence: 99%

Narrating Perinatal Obsessive-Compulsive Disorder Through Blogs

Beck¹

2022

McN: The American Journal of Maternal/Child Nursing

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To describe women's experiences of perinatal obsessivecompulsive disorder (OCD) as written in their blogs. Study Design and Method: This qualitative descriptive study examined perinatal OCD blogs identifi ed using Google search engine. Krippendorff's thematic content analysis method for qualitative data was used. The unit of analysis included segments of the bloggers' descriptions of their perinatal OCD. Clustering and dendrograms were used to group the data into themes. Results: Forty-three different posts from women in the United Kingdom, United States, Australia, and South Africa were analyzed. Five themes were identifi ed that described women's experiences of perinatal OCD as told in their blogs: (1) Starting to tighten its grip during pregnancy, (2) Keeping horrifi c secrets all to themselves, (3) Tortured with terrifying images and thoughts, (4) Driven to compul-

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Birth weight and gestational age in newborns exposed to maternal obsessive-compulsive disorder

Cited by 16 publications

References 18 publications

Elevated risk for obsessive–compulsive symptoms in women pregnant during the COVID-19 pandemic

Elevated risk for obsessive–compulsive symptoms in women pregnant during the COVID-19 pandemic

Obsessive-compulsive disorder in pregnancy and the postpartum period: course of illness and obstetrical outcome

Narrating Perinatal Obsessive-Compulsive Disorder Through Blogs

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