Birth size effect on pulmonary functions and atopic sensitization in preadolescence

Bostancı, İlknur; Díllí, Dílek; Dallar, Yıldız

doi:10.1111/j.1442-200x.2008.02631.x

Cited by 3 publications

(3 citation statements)

References 26 publications

(43 reference statements)

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“…Some were born extremely preterm, whereas others of a lesser degree of prematurity had birth weights of 1500 g or less because of poor intrauterine growth. Two previous studies reported no difference in predisposition for atopy between subjects born small or of 44,45 whereas we found higher rates of atopy among those born small for gestational age.…”

Section: Discussioncontrasting

confidence: 86%

Preterm birth reduces the incidence of atopy in adulthood

Siltanen

Wehkalampi

Hovi

et al. 2011

Journal of Allergy and Clinical Immunology

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Section: Discussioncontrasting

confidence: 86%

Preterm birth reduces the incidence of atopy in adulthood

Siltanen

Wehkalampi

Hovi

et al. 2011

Journal of Allergy and Clinical Immunology

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“…Significant interest has focused on the possibility of predicting and preventing atopic disorders among children during pregnancy and infancy. Serum total IgE levels were higher in preadolescent SGA children than in AGA children, although there was no significant difference between the 2 groups in terms of atopy (Bostanci et al, 2008). These findings suggest that both environmental and genetic factors determine the level of serum IgE.…”

Section: Discussionmentioning

confidence: 62%

“…These findings suggest that both environmental and genetic factors determine the level of serum IgE. It has been hypothesized that when the demand for nutrients later in gestation no longer fully meet the needs of the rapidly growing fetus, the differentiation of specific thymus-derived helper lymphocytes from T-helper 2 type toward T-helper 1 type lymphocytes may be permanently impaired, leading to exaggerated IgE responses and atopic disease phenomena later in life (Godfrey et al, 1994;Bostanci et al, 2008;Hinz et al, 2010), although some findings are inconsistent. In our study, we found no association between IgE and atopic disease later in life, and the mechanism underlying FGR and atopic disease must be further explored.…”

Section: Discussionmentioning

confidence: 99%

Serum immunoglobulin E level and its impact on the pregnancy outcome associated with fetal growth restriction: a prospective cohort study

Xiong¹,

Tong²,

Li³

et al. 2015

Genet. Mol. Res.

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ABSTRACT. We evaluated the relationship between total serum immunoglobulin E (IgE) levels and pregnancy outcome in a prospective cohort study focusing on fetal growth restriction (FGR). Sixty women with FGR and twenty with normal singleton pregnancy were enrolled during their third trimester. Infants were followed up for 6 months. Blood samples were obtained from pregnant women during the third trimester; cord blood samples were also taken. Six months after birth, blood samples were obtained from infants. Demographic and baseline characteristics were compared between groups. Birth weight, length and head circumference of neonates in the FGR group were lower than those in the control group. Total serum IgE level was significantly increased in third-trimester pregnant women with FGR compared with normal group (P < 0.05). However, this trend was not observed in the cord blood at birth or peripheral blood of 6-month-old infants. The prevalence of atopic eczema between the 2 groups was similar. Linear regression analysis revealed that the IgE level in the third trimester was negatively correlated with birth weight (P < 0.05). Higher serum IgE level in the cord blood was significantly associated with an increased risk of being small for gestational age (P < 0.05). In conclusion, IgE levels in the third trimester of pregnancy and cord blood are strongly related to birth outcomes of FGR.

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Food Allergy Among Low Birthweight Children in a National Survey

Chandran

Demissie²,

Echeverría³

et al. 2012

Matern Child Health J

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The aim of this paper was to investigate the association between birthweight and prevalence of food allergies using a national sample of US children. Adult report of birthweight and child food allergies were obtained for years 2005-2009 from the National Health Interview Survey (NHIS), a cross-sectional household survey of the US population. A total of 51,748 children aged 0-17 years were included in the analyses representing over 73 million children. Multivariable logistic regression analyses examined associations between birthweight categories and food allergies stratified by age and gender; accounting for the complex design of NHIS. Children aged 6-12 years who were born very low birthweight (500-1,499 g) were more likely to have reported food allergy compared to referent (3,000-3,499 g), OR = 1.72; 95% CI: 1.02-2.91. However, there was no clear trend of an association between birthweight and food allergy with increasing or decreasing birthweight across all ages. Estimates were generally stronger in younger male children as compared to estimates in females of the same age group. Marginal associations for respiratory allergy (OR = 1.52; 95% CI: 1.02-2.29) and hay fever (OR = 1.54; 95% CI: 0.93-2.54) were observed among very low birthweight children aged 0-5 years. There was limited evidence for a clear association between birthweight and food allergy. Marginal associations observed in children weighing 500-1,499 g at birth support efforts to minimize preterm births and very low birthweight given the increase in pediatric food allergies and the large number of children born low birthweight each year in the US.

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Birth size effect on pulmonary functions and atopic sensitization in preadolescence

Cited by 3 publications

References 26 publications

Preterm birth reduces the incidence of atopy in adulthood

Preterm birth reduces the incidence of atopy in adulthood

Serum immunoglobulin E level and its impact on the pregnancy outcome associated with fetal growth restriction: a prospective cohort study

Food Allergy Among Low Birthweight Children in a National Survey

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