Bipolarité cachée dans le trouble obsessionnel compulsif : enquête collaborative avec l’Association française des personnes souffrant de TOC (AFTOC)

Obsessive-compulsive syndromes and disorders

“…We found associations between OCS* and bipolar disorder (mainly BP-II), anxiety (panic and GAD) and social phobia; in contrast to two other epidemiological studies (Grabe et al 2001;Karno et al 1988) we found no associations with major depressive disorders. The latter findings are compatible with several other studies, which stressed the importance of BP disorders in OCD comorbidity (Chen and Dilsaver 1995;Hantouche et al 2002aHantouche et al , 2003Kruger et al 1995;Perugi et al 1997aPerugi et al , 1999. We a s s ume that our wide definition of BP II disorders reduced the habitual over-diagnosis of major depressive disorders (MDD) so far that the co-occurrence of OCS* with pure MDD became negligible.…”

“…A lack of association between OCS* and depression was also confirmed by our analyses of depressive spectra (including bipolar and unipolar dysthymia, minor and recurrent brief depression).This negative finding is consistent with results of another analysis in the Zurich study, which showed that a broad definition of BP-II disorders shifted the alcohol comorbidity from major depression to bipolar-II disorder (Angst et al in preparation). OCS* is also common in soft bipolar conditions, such as bipolar-II disorder, brief recurrent hypomania or cyclothymic temperament, as shown by a French study conducted in collaboration with the AFTOC (French Association of OCD patients) (Hantouche et al 2002a).…”