Biphenyls and xanthones from the podostemaceae

Biphenyls from Berberis koreana

“…Purification of the n-hexane extract led to the isolation of 14 biphenyl derivatives (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14). Among these, the known compounds were identified as the previously reported substances eriobofuran (4), 11 methoxyaucuparin (5), 1 3,5-dimethoxybiphenyl-2′-ol (6), 21 3-hydroxy-5methoxybiphenyl (7), 22 aucuparin (8), 23 3,5-dimethoxybiphenyl (9), 24 3,5-dimethoxybiphenyl-4′-ol (10), 25 2′-hydroxyaucuparin (11), 23 δ-cotonefuran (12), 11 9-hydroxyeriobofuran (13), 11 and ε-cotonefuran (14), 10 by comparison of their spectroscopic and physical data with previously reported values.…”

“…The 13 C NMR spectroscopic data (including HMQC and DEPT) indicated 24 carbon signals of 1 to be composed of 18 aromatic carbons (including nine quaternary carbons), two oxygenated methine carbons, an oxygenated methylene carbon, and three methoxy carbons. The signals for a monosubstituted benzene ring [δ C 141.0 (C-1′), 128.9 (C-3′, 5′), 127.3 (C-4′), 127.0 (C-2′, 6′)], a 1,3,4,5-tetrasubstituted benzene ring [δ C 149.2 (C-3), 144.7 (C-5), 134.3 (C-1), 132.7 (C-4), 108.9 (C-6), 103.7 (C-2)], and a methoxy group [δ C 56.4 (OCH 3 -3)] implied that compound 1 is a biphenyl derivative on the basis of its NMR data. − This was reconfirmed by the HMBC spectrum (Figure ). Additionally, the signals for a 1,3,4,5-tetrasubstituted benzene ring [δ C 147.5 (C-3′′, 5′′), 135.5 (C-1′′), 128.2 (C-4′′), 104.3 (C-2′′, 6′′)/δ H 6.72 (H-2′′, 6′′)], a 1-substituted 1,2,3-propantriol [δ C 78.7 (C-8′′), 76.5 (C-7′′), 61.7 (C-9′′)/δ H 5.02 (H-7′′), 4.05 (H-8′′), 3.93 (H-9′′a), 3.61 (H-9′′b)], and two methoxy groups [δ C 56.6 (OCH 3 -3′′, 5′′)/δ H 3.94 (OCH 3 -3′′, 5′′)] were observed.…”

A new biphenyl from Clusia melchiorii and a new tocotrienol from C. obdeltifolia

“…The irradiation of methoxyl hydrogens of 2 enhanced the signal of H-4' allowing to locate unambiguously the dimethylpyrane ring at C-3 and C-4 and not at C-2 and C-3 ( Figure 1). Compound 2 had been previously isolated from Mourera fluviatilis 18 along with its isomer with the dimethylpyrane ring at C-2 and C-3. The authors differentiated the two isomers using an argument based only in the analysis of 1 H chemical shifts differences for the meta-coupled aromatic hydrogens.…”

Vasorelaxant and hypotensive effects of the extract and the isolated flavonoid rutin obtained from Polygala paniculata L.

“…Rutin was the only flavonoid identified in the hydroalcoholic extract from P. paniculata (HEPP) and was found to be the major compound of the extract (0.17% of extract). The identification of all compounds was performed with various spectroscopic analyses (EIMS, IR, 1 H and 13 C NMR/DEPT, HMQC, HMBC and NOE) [7,28–30] …”

“…The identification of all compounds was performed with various spectroscopic analyses (EIMS, IR, 1 H and 13 C NMR/DEPT, HMQC, HMBC and NOE). [7,[28][29][30]…”