Biotransformation of an antimalarial drug, artemether by plant and fungal cell cultures

Biotransformation of 4-methylcoumarins by cambial meristematic cells of Camptotheca acuminata

“…10 Biotransformation catalyzed by biocatalysts, including enzymes, whole cells, or microorganisms, is widely used for biological structural modication with regio-and stereoselectivity, and this process has great potential to generate soluble and non-toxic metabolites via mild reaction conditions and fewer steps. [11][12][13][14] Several studies on the bioconversion of coumarins in plant cells have been reported. Nine hydroxycoumarins with different substituted groups were biotransformed to investigate the substrate specicity and regioselectivity of coumarin glycosyltransferases in the hairy roots of Polygonum multiorum.…”

In-vitro immunomodulatory and anti-cancerous activities of biotransformed products of Dianabol through Azadirachta indica and its molecular docking studies

“…A . indica has not used before for the structural modification of organic compounds except our group [ 13 - 15 ]. A .…”

Biotransformation of Finasteride by Ocimum sanctum L., and tyrosinase inhibitory activity of transformed metabolites: Experimental and computational insights

“…a-Santonin, a 54 eudesmanolide compound, was biotransformed by five different 55 plant cells suspension into different derivatives [5]. In addition, 56 the biotransformation of (À) -ambrox and artemether by Peganum 57 harmala and Azadirachta indica, respectively, have been reported 58 [6,7] 500 MHz) see Table 2, and 13 C NMR (CD 3 OD, 125 MHz) see …”