Biotechnological Potential of Rhodococcus Biodegradative Pathways

Abstract

The genus Rhodococcus is a phylogenetically and catabolically diverse group that has been isolated from diverse environments, including polar and alpine regions, for its versatile ability to degrade a wide variety of natural and synthetic organic compounds. Their metabolic capacity and diversity result from their diverse catabolic genes, which are believed to be obtained through frequent recombination events mediated by large catabolic plasmids. Many rhodococci have been used commercially for the biodegradation of environmental pollutants and for the biocatalytic production of high-value chemicals from low-value materials. Recent studies of their physiology, metabolism, and genome have broadened our knowledge regarding the diverse biotechnological applications that exploit their catabolic enzymes and pathways.

Research Note: Increase of bad bacteria and decrease of good bacteria in the gut of layers with vs. without hepatic steatosis

“…Rhodococcus genus is also a conditional pathogen, which has strong infection ability under specific conditions. It has been reported that Rhodococcus genus is related to the case of human immune dysfunction ( Kim et al., 2018 ). In summary, there were more bacteria that can inhibit host energy absorption and benefit intestinal health in the ileum of the group without hepatic steatosis, whereas there were more conditional pathogens or harmful bacteria in the ileum of the group with hepatic steatosis.…”

Complete Genome Sequence of Rhodococcus ruber R1, a Novel Strain Showing a Broad Catabolic Potential toward Lignin-Derived Aromatics

“…M embers of the Rhodococcus genus are aerobic, GC-rich, Gram-positive bacteria belonging to the actinomycetes (1), whose recognized capacity to degrade hydrocarbons suggests that they might be useful in lignin biodegradation (2)(3)(4)(5). Here, we report the complete genome sequence of Rhodococcus ruber R1, an actinobacterium with the ability to grow on several phenolics as the sole carbon source (Fig.…”

Re‐Investigation of Hydration Potential of Rhodococcus Whole‐Cell Biocatalysts towards Michael Acceptors

“…Rhodococcus is a genus of a gram‐positive bacteria that has been described to host a variety of enzymes and degradation pathways with high potential for the use in industrial processes . Its metabolic diversity often stems from large, linear plasmids that carry the protein‐encoding genes for degradative enzyme systems . Abundant horizontal gene‐transfer events occurring via these linear plasmids as well as a high multiplicity of catabolic enzymes contributed to the catabolic versatility of Rhodococcus genus members …”

“…[8,14] Its metabolic diversity often stems from large, linear plasmids that carry the protein-encoding genes for degradative enzyme systems. [15] Abundant horizontal genetransfer events occurring via these linear plasmids as well as a high multiplicity of catabolic enzymes contributed to the catabolic versatility of Rhodococcus genus members. [15][16][17] To study the described water addition in-depth, the identification and isolation of the responsible enzyme were first aimed for.…”

“…[15] Abundant horizontal genetransfer events occurring via these linear plasmids as well as a high multiplicity of catabolic enzymes contributed to the catabolic versatility of Rhodococcus genus members. [15][16][17] To study the described water addition in-depth, the identification and isolation of the responsible enzyme were first aimed for. Due to complications in the protein isolation, wholecell systems were further investigated to explore the substrate range.…”