Biotechnological approaches for the production of camptothecin
Akshatha Banadka,
Sudheer Wudali Narasimha,
Vijayalaxmi S. Dandin
et al.
Abstract:Camptothecin (CPT), an indole alkaloid popular for its anticancer property, is considered the third most promising drug after taxol and famous alkaloids from Vinca for the treatment of cancer in humans. Camptothecin was first identified in Camptotheca acuminata followed by several other plant species and endophytic fungi. Increased harvesting driven by rising global demand is depleting the availability of elite plant genotypes, such as Camptotheca acuminata and Nothapodytes nimmoniana, crucial for producing al… Show more
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