Biosynthesis of silver nanoparticles from novel Bischofia javanica plant loaded chitosan hydrogel: as antimicrobial and wound healing agent

Rafiq, Aftab; Tehseen, Saimoon; Khan, Taskeen Ali; Awais, Muhammad; Sodhozai, Asma Rabbani; Javed, Chaudhary Hassan; Ullah, Muhammad Farhat; Ali, Naeem; Alshahrani, Mohammad Y.; Khan, M. Ijaz; Galal, Ahmed M.

doi:10.1007/s13399-022-02960-w

Cited by 7 publications

(3 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to their results, Col-AgNPs can increase antimicrobial activity and cell biocompatibility more than colistin and AgNPs [51]. In their in vitro studies with silver nanoparticles to investigate antimicrobial activity, Rafq et al reported that diferent concentrations of silver nanoparticles were efective against diferent microorganisms, such as bacteria (E. coli, S. aureus, P. aeruginosa, and K. pneumoniae) and fungi (C. albicans) [52]. AgNPs synthesized from aqueous leaf extracts of Galphimia glauca were found to have efective antimicrobial activity against Pseudomonas aeruginosa and Candida glabrata [53].…”

Section: Antimicrobial Activity Antimicrobial Activities Ofmentioning

confidence: 99%

Synthesis and Characterization of Paclitaxel-Loaded Silver Nanoparticles: Evaluation of Cytotoxic Effects and Antimicrobial Activity

Tunç,

Hepokur,

Kari̇per

2024

Bioinorganic Chemistry and Applications

View full text Add to dashboard Cite

Carrier system therapies based on combining cancer drugs with nanoparticles have been reported to control tumor growth and significantly reduce the side effects of cancer drugs. We thought that paclitaxel-loaded silver nanoparticles (AgNPs-PTX) were the right carrier to target cancer cells. We also carried out antimicrobial activity experiments as systems formed with nanoparticles have been shown to have antimicrobial activity. In our study, we used easy-to-synthesize and low-cost silver nanoparticles (AgNPs) with biocatalytic and photocatalytic advantages as drug carriers. We investigated the antiproliferative activities of silver nanoparticles synthesized by adding paclitaxel on MCF-7 (breast adenocarcinoma cell line), A549 (lung carcinoma cell line), C6 (brain glioma cell line) cells, and healthy WI-38 (fibroblast normal cell line) cell lines and their antimicrobial activities on 10 different microorganisms. The synthesized AgNPs and AgNPs-PTX were characterized by dynamic light scattering (DLS), scanning transmission electron microscopy, UV-visible spectroscopy, Fourier transform infrared spectroscopy, and X-ray spectroscopy. The nanoparticles were spherical in shape, with AgNPs ranging in size from 2.32 to 5.6 nm and AgNPs-PTXs from 24.36 to 58.77 nm. AgNPs demonstrated well stability of −47.3 mV, and AgNPs-PTX showed good stability of −25.4 mV. The antiproliferative effects of the synthesized nanoparticles were determined by XTT (tetrazolium dye; 2,3-bis-(2-methoxy-4-nitro-5-sulfenyl)-(2H)-tetrazolium-5-carboxanilide), and the proapoptotic effects were determined by annexin V/propidium iodide (PI) staining. The effect of AgNPs-PTX was more effective, and anticancer activity was higher than PTX in all cell lines. When selectivity indices were calculated, AgNPs-PTX was more selective in the A549 cell line (SI value 6.53 μg/mL). AgNPs-PTX was determined to increase apoptosis cells by inducing DNA fragmentation. To determine the antimicrobial activity, the MIC (minimum inhibitory concentration) test was performed using 8 different bacteria and 2 different fungi. Seven of the 10 microorganisms tested exhibited high antimicrobial activity according to the MIC ≤100 μg/mL standard, reaching MIC values below 100 μg/mL and 100 μg/mL for both AgNPs and AgNPs-PTX compared to reference sources. Compared to standard antibiotics, AgNPs-PTX was highly effective against 4 microorganisms.

show abstract

Section: Antimicrobial Activity Antimicrobial Activities Ofmentioning

confidence: 99%

Synthesis and Characterization of Paclitaxel-Loaded Silver Nanoparticles: Evaluation of Cytotoxic Effects and Antimicrobial Activity

Tunç,

Hepokur,

Kari̇per

2024

Bioinorganic Chemistry and Applications

View full text Add to dashboard Cite

show abstract

“…According to these results, the peak of the 3309 cm À 1 OH hydroxyl group, [30] CÀ H stress containing 1620 cm À 1 aliphatic alkanes [39] , and the peaks with 1008 cm À 1 CÀ O vibration [40] are seen as common peaks in these plant parts. The peaks of 2984 cm À 1 and 2916 cm À 1 have CÀ H vibrations of alkane carbons.…”

Section: Atr-ftir Profilementioning

confidence: 99%

“…Stearic acid, which is the major ingredient in flowers and tubers, is present in higher amounts than in seeds. The Venn network in Figure 3 represents the fatty acid composition Polysaccharides, [30,31] 2916-2984 2984 2984 2916 À CH 2 stretching vibrations, Polysaccharides; Lipids, Lignin, [32] 1731-1743 --1734 C=O stretching vibration of carboxyl and acetyl group,…”

Section: Fatty Acid Analysis Quantity and Gc-ms Analysis Of Methanol ...mentioning

confidence: 99%

Phytochemical Analysis of Anacamptis coriophora Plant Cultivated Using Ex Vitro Symbiotic Propagation

Aytar,

Harzli,

Özdener Kömpe

2023

Chemistry & Biodiversity

View full text Add to dashboard Cite

This study aims to investigate the functional groups and phytochemical profile of Anacamptis coriophora seeds, tubers, and flowers. Symbiotic seedlings produced using the ex vitro method were transferred to their natural habitat and grown to analyze the functional groups and phytochemical profiles of tubers and flowers. The life cycles of the transferred seedlings were monitored, and tubers and flowers were harvested for analysis. ATR‐FTIR spectroscopy revealed the presence of functional groups such as polysaccharides, lignin, and proteins in both tubers and flowers. Differences in spectral frequencies between first‐year and second‐year tubers were observed. Fatty acid analysis identified 30 different compounds in seeds, flowers, and tubers, with linoleic acid being the most abundant (27% in seeds, 33% in tubers), and palmitic acid present in flowers (24%). GC‐MS analysis of ethanol extracts from these components highlighted the presence of 32 compounds, including hydroxyacetic acid, hydrazide, cytidine (Z)‐7‐hexadecenal, 2,2‐dimethoxyethane, 2,5,6‐trimethyldecane, and butanamide, 4‐amino‐N‐hydroxy. A. coriophora's tubers, flowers, and seeds may contain active metabolites with therapeutic potential. These results are valuable for the commercial cultivation of the plant.

show abstract

Multiple response behaviors of curcumin-loaded ammonium alginate/polyvinyl alcohol hydrogel and its application

Cai

Zhong

Tang

et al. 2023

Biomass Conv. Bioref.

View full text Add to dashboard Cite

Biosynthesis of silver nanoparticles from novel Bischofia javanica plant loaded chitosan hydrogel: as antimicrobial and wound healing agent

Cited by 7 publications

References 54 publications

Synthesis and Characterization of Paclitaxel-Loaded Silver Nanoparticles: Evaluation of Cytotoxic Effects and Antimicrobial Activity

Synthesis and Characterization of Paclitaxel-Loaded Silver Nanoparticles: Evaluation of Cytotoxic Effects and Antimicrobial Activity

Phytochemical Analysis of Anacamptis coriophora Plant Cultivated Using Ex Vitro Symbiotic Propagation

Multiple response behaviors of curcumin-loaded ammonium alginate/polyvinyl alcohol hydrogel and its application

Contact Info

Product

Resources

About