Biosynthesis of melanotropins and endorphins by the lead-haematoxylin positive cells in pars intermedia of the cichlid teleost Sarotherodon mossambicus
Abstract:Abstract-1. Biosynthesis in the lead-haematoxylin positive pars intermedia cells of Sarotherodon mossambicus was analysed by SDS and acid-urea electrophoresis and high pressure liquid chromatography.2. Pulse and pulse-chase experiments revealed that a non-glycosylated 30K-precursor was processed into a number of smaller products.3. Melanotropic and endorphin-like peptides appeared to be the final products of this precursor-product processing.4. Our results indicate that the biosynthetic pathways in the lead-ha… Show more
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