Biosynthesis of Copper Nanoparticles with Medicinal Plants Extracts: From Extraction Methods to Applications

Abstract

Copper nanoparticles (CuNPs) can be synthesized by green methods using plant extracts. These methods are more environmentally friendly and offer improved properties of the synthesized NPs in terms of biocompatibility and functional capabilities. Traditional medicine has a rich history of utilization of herbs for millennia, offering a viable alternative or complementary option to conventional pharmacological medications. Plants of traditional herbal use or those with medicinal properties are candidates to be used to obtain NPs due to their high and complex content of biocompounds with different redox capacities that provide a dynamic reaction environment for NP synthesis. Other synthesis conditions, such as salt precursor concentration, temperature, time synthesis, and pH, have a significant effect on the characteristics of the NPs. This paper will review the properties of some compounds from medicinal plants, plant extract obtention methods alternatives, characteristics of plant extracts, and how they relate to the NP synthesis process. Additionally, the document includes diverse applications associated with CuNPs, starting from antibacterial properties to potential applications in metabolic disease treatment, vegetable tissue culture, therapy, and cardioprotective effect, among others.

Development of CuO Nanoparticles from the Mucus of Garden Snail Cornu aspersum as New Antimicrobial Agents

“…Many reports of antibacterial, antifungal, larvicidal, anti-termite [ 61 , 62 , 63 , 64 , 65 ], and anticancer [ 66 , 67 ] activities of CuONPs derived from plants, animals, and microorganisms. Furthermore, several studies conducted in recent years have demonstrated the advantages of employing snail mucus to synthesize Ag and AuNPs, which have been shown to have broad-spectrum antibacterial activity, anticancer potential, and anti-inflammatory properties [ 21 , 68 ].…”

Nardostachys jatamansi: A Review on Extraction Isolation Bioactivities of Phytoconstituents Chemical Structures and Traditional Uses

“…A concentrated extract was created by cooling the liquid extract after extraction and using a rotary evaporator to concentrate the solvent content. [11][12][13] The method for isolating and purifying bioactive compounds is as follows: [14][15][16][17] Extraction This is the initial step where solvents extract bioactive compounds from the natural source material. Different solvents can be used depending on the targeted compounds' properties.…”

Exploring the potential of a Ephedra alata leaf extract: Phytochemical analysis, antioxidant activity, antibacterial properties, and green synthesis of ZnO nanoparticles for photocatalytic degradation of methylene blue

“…Ephedra alata leaves contain various phytochemicals, including flavonoids, alkaloids and phenolic compounds. These leaves have been used as reducing and capping agents for the synthesis of gold, silver, and copper oxide NPs ( Mousavi et al, 2018 ; Al-Radadi, 2023 ; Antonio-Pérez et al, 2023 ; Atri et al, 2023 ; Bouzid et al, 2023 ). Therefore, Ephedra alata extracts could be used for NP production in order to address the concerns associated with the very high toxicity of conventional NP production systems that poses risks to human and animal health.…”