Biosynthesis, characterization and antioxidant activity of oleuropein-mediated silver nanoparticles

Genç, Nusret; Yildiz, İlyas; Chaoui, Radia; Erenler, Ram­azan; Elmastaş, Mahfuz

doi:10.1080/24701556.2020.1792495

Cited by 48 publications

(16 citation statements)

References 28 publications

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“…After completion of the reaction, Sa-AgNPs were obtained by repeated centrifugation at 5000 rpm for 20 minutes then washed thoroughly with distilled water. The Sa-AgNps were dried by lyophilisation [7].…”

Section: Synthesis Of Silver Nanoparticlesmentioning

confidence: 99%

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Green Synthesis of Silver Nanoparticles from Salvia aethiopis L. and Their Antioxidant Activity

Geçer

2021

J Inorg Organomet Polym

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Salvia aethiopis L. was heated in distilled water for 2 hours. After ltration, water extract was treated with silver nitrate for 2 hours at 60°C to yield the silver nanoparticles (Sa-AgNPs). The structure of silver nanoparticles was elucidated by spectroscopic methods such as Ultraviolet-visible (UV-Vis), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and Scanning electron microscope (SEM). The maximum absorption in UV-Vis spectrum was observed at 508 nm. XRD pattern at (2θ) 38.1°, 44.3°, 64.4°, and 77.4° degrees can be assigned to the (111), ( 200), ( 220) and (311) Bragg's re ections of the face-centered cubic crystalline structure. The average size of Sa-AgNPs was found as 74.09 nm by SEM analysis. The characteristic hydroxyl vibration signal appeared at 3222 cm − 1 . Antioxidant activity of extract and Sa-AgNPs were carried out using DPPH • , ABTS •+ FRAP assay. The Sa-AgNPs revealed the considerable ABTS •+ scavenging effect with the value of 4.93 (IC 50 , µg/mL) compared to BHT (IC 50 , µg/mL, 8.34). However, Sa-AgNPs displayed the lower DPPH • activity (IC 50 , µg/mL, 24.37) than that of the standard BHT (IC 50 , µg/mL, 9.67). The reducing power activity of Sa-AgNPs was found as 4.52 (µmol TE/mg extract) while the standard BHT value was 488 (µmol TE/mg extract).

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Section: Synthesis Of Silver Nanoparticlesmentioning

confidence: 99%

“…However, these methods lead to environmental contamination, toxic residue, and high cost. Therefore, natural products gain great interest in the synthesis of nanoparticles due to their eco-friendly, low cost, high e ciency, and scale-up properties [6,7].…”

Section: Introductionmentioning

confidence: 99%

Green Synthesis of Silver Nanoparticles from Salvia aethiopis L. and Their Antioxidant Activity

Geçer

2021

J Inorg Organomet Polym

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“…Several clinical and preclinical studies conducted have identified its beneficial role against different human diseases. OL have been found to exhibit many pharmacological and biological effects such as cardioprotective (Çömez et al., 2020; Zhao et al., 2017), antidiabetic (Kamİloğlu et al., 2019; Karabag‐Coban et al., 2017), hypolipidemic (Malliou et al., 2018), antiischemic (Esmailidehaj et al., 2016; Zhang et al., 2018), antioxidant (Ivanov et al., 2018), anti‐inflammatory (Janahmadi et al., 2017), anticancer (Przychodzen et al., 2019), hepatoprotective (Cerig et al., 2016), nephroprotective (Geyikoglu et al., 2017), and neuroprotective actions (Benlarbi et al., 2020). The current review presents precise information about the chemistry, biosynthesis, and bioavailability of OL alongside an updated vision from the past decade about its neuroprotective role in counteracting the acute and chronic NDDs and NPDs.…”

Section: Introductionmentioning

confidence: 99%

Neuroprotective effects of oleuropein: Recent developments and contemporary research

et al. 2021

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Neurological disorders are increasing at a faster pace due to oxidative stress, protein aggregation, excitotoxicity, and neuroinflammation. It is reported that the Mediterranean diet including olives as a major dietary component prevents and ameliorates neurological anomalies. Oleuropein is the major bioactive component in different parts of the Olive (Olea europaea L.) tree. Several mechanisms have been reported for the neuroprotective role of oleuropein including induction of apoptosis and autophagy, enhancing the antioxidant pool of the cerebral region, decreasing the unnecessary release of proinflammatory cytokines and chemokines by deactivating the microglia cells and astrocytes thus preventing the occurrence of neuroinflammation. Regular intake of oleuropein seems to be correlated with decreased risks of neural disorders including Alzheimer's, Parkinson's, strokes, depression, anxiety, epilepsy, and others. This review majorly discusses the chemistry, biosynthesis, and metabolism of oleuropein along with an updated vision of its neuroprotective role in counteracting the acute and chronic neurodegenerative and neuropsychiatric disorders. Moreover, mechanisms by which oleuropein may prevent neurodegeneration are reviewed. Practical application Neurological disorders are negatively affecting the health and life quality of individuals around the globe. Although various medicinal solutions are available to tackle such ailments, none has proven to fully cure and being deprived of side effects. In this respect, the prevention of such disorders using natural remedies may be an effective strategy to overcome the incidence of the increasing cases. Furthermore, the natural compounds provide a safer alternative to pharmaceutical drugs. Hence, oleuropein from olive tree products is found to be efficacious against neurological disorders. This review provides an updated insight on the positive effects of oleuropein against neurodegenerative and neuropsychiatric disorders. The diet practitioners and nutraceutical companies may benefit from the provided information to design and develop strategies to improve the mental health of suffering individuals.

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“…The bands observed at 1690 and 1636 cm −1 are attributed to the characteristic vibration of the two carbonyl groups in the oleuropein molecule. The C=C has a stretching vibration at 1515 cm −1 and bending vibration at 853 cm −1 [45]. The bands at 1440 and 1376 cm −1 are due to a bending vibration of O-H. Strong stretching C-O vibrations are observed at 1267, 1161, 1070 , and 1032 cm −1 .…”

Section: Resultsmentioning

confidence: 96%

HPTLC and FTIR Fingerprinting of Olive Leaves Extracts and ATR-FTIR Characterisation of Major Flavonoids and Polyphenolics

et al. 2021

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The aim of this study was to analyse the effect of spontaneous microbial maceration on the release and extraction of the flavonoids and phenolics from olive leaves. Bioprofiling based on thin-layer chromatography effect-directed detection followed by ATR-FTIR spectroscopy proved to be a reliable and convenient method for simultaneous comparison of the extracts. Results show that fermentation significantly enhances the extraction of phenolic compounds and flavonoids. The polyphenolic content was increased from 6.7 µg GAE (gallic acid equivalents) to 25.5 µg GAE, antioxidants from 10.3 µg GAE to 25.3 µg GAE, and flavonoid content from 42 µg RE (rutin equivalents) to 238 µg RE per 20 µL of extract. Increased antioxidant activity of fermented ethyl acetate extracts was attributed to the higher concentration of extracted flavonoids and phenolic terpenoids, while increased antioxidant activity in fermented ethanol extract was due to increased extraction of flavonoids as extraction of phenolic compounds was not improved. Lactic acid that is released during fermentation and glycine present in the olive leaves form a natural deep eutectic solvent (NADES) with significantly increased solubility for flavonoids.

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Biosynthesis, characterization and antioxidant activity of oleuropein-mediated silver nanoparticles

Cited by 48 publications

References 28 publications

Green Synthesis of Silver Nanoparticles from Salvia aethiopis L. and Their Antioxidant Activity

Green Synthesis of Silver Nanoparticles from Salvia aethiopis L. and Their Antioxidant Activity

Neuroprotective effects of oleuropein: Recent developments and contemporary research

HPTLC and FTIR Fingerprinting of Olive Leaves Extracts and ATR-FTIR Characterisation of Major Flavonoids and Polyphenolics

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