Biosurfactants: the next generation biomolecules for diverse applications

Rawat, Geeta; Dhasmana, Anupam; Kumar, Vivek

doi:10.1007/s42398-020-00128-8

Cited by 39 publications

(27 citation statements)

References 209 publications

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“…Insecticides, herbicides, rodenticides, and fungicides are among the most regularly used pesticides ( Malla et al, 2018 ) and were used excessively during the green revolution to increase productivity and reduce crop loss ( Sarath Chandran et al, 2019 ). Pesticide use is rising and negatively influencing the environment, particularly the soil quality and health ( Rawat et al, 2020 ), as only 1% of sprayed pesticides kill target species; the rest pollute the ecosystem by interacting with soil and generating more complex metabolites. For example, chlorpyrifos produces 3,5,6-trichloro-2-pyridinon (TCP), an antimicrobial metabolite that kills beneficial soil microorganisms and due to its eco-toxicity, the United nation banned this pesticide in the year 2020.…”

Section: Emerging Pesticide Pollution: a Global Concernmentioning

confidence: 99%

“…Biosurfactants which are surface-active molecules produced naturally by microbial metabolism have gained popularity in recent times. In recent years, there has been a steady increase in the number of research papers focused on the isolation, characterization, and optimization of biosurfactants producing microbes ( Das and Kumar, 2018 ; Olasanmi and Thring, 2018 ; Khanna and Pattnaik, 2019 ; Rawat et al, 2020 ). Biosurfactants are the type of “glycoconjugates (combination of glycoprotein and glycolipids),” and the study of its structure, function, and interaction with the living system is called “glycobiotechnology” ( Messner et al, 2013 ; Enaime et al, 2019 ).…”

Section: Biosurfactants: the Next Age Compounds In Pesticide Remediation And Their Typesmentioning

confidence: 99%

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Tapping the Role of Microbial Biosurfactants in Pesticide Remediation: An Eco-Friendly Approach for Environmental Sustainability

2021

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Pesticides are used indiscriminately all over the world to protect crops from pests and pathogens. If they are used in excess, they contaminate the soil and water bodies and negatively affect human health and the environment. However, bioremediation is the most viable option to deal with these pollutants, but it has certain limitations. Therefore, harnessing the role of microbial biosurfactants in pesticide remediation is a promising approach. Biosurfactants are the amphiphilic compounds that can help to increase the bioavailability of pesticides, and speeds up the bioremediation process. Biosurfactants lower the surface area and interfacial tension of immiscible fluids and boost the solubility and sorption of hydrophobic pesticide contaminants. They have the property of biodegradability, low toxicity, high selectivity, and broad action spectrum under extreme pH, temperature, and salinity conditions, as well as a low critical micelle concentration (CMC). All these factors can augment the process of pesticide remediation. Application of metagenomic and in-silico tools would help by rapidly characterizing pesticide degrading microorganisms at a taxonomic and functional level. A comprehensive review of the literature shows that the role of biosurfactants in the biological remediation of pesticides has received limited attention. Therefore, this article is intended to provide a detailed overview of the role of various biosurfactants in improving pesticide remediation as well as different methods used for the detection of microbial biosurfactants. Additionally, this article covers the role of advanced metagenomics tools in characterizing the biosurfactant producing pesticide degrading microbes from different environments.

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Section: Emerging Pesticide Pollution: a Global Concernmentioning

confidence: 99%

Section: Biosurfactants: the Next Age Compounds In Pesticide Remediation And Their Typesmentioning

confidence: 99%

Tapping the Role of Microbial Biosurfactants in Pesticide Remediation: An Eco-Friendly Approach for Environmental Sustainability

2021

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“…Lipopeptide procured from Bacillus subtilis CN2 exhibits stability spanning a range of temperature between 25 and 125 °C, with pH and salinity of scale 5-12 pH, and 5-20% w/v, respectively (Bezza and Chirwa 2015a). On the contrary to chemical surfactants, microbially originated surfactants possess the ability to degrade rapidly, making them applicable for environmental processes such as bioremediation and waste management (Kuyukina and Ivshina 2019;Rawat et al 2020;Castelein et al 2021). The degradation is improved by up to 46% of higher alkanes having the carbon atom from C10 to C24 by glycolipid produced from the synergistic effect of Pseudozyma sp.…”

Section: Properties Of Biosurfactantsmentioning

confidence: 99%

Extraction, purification and applications of biosurfactants based on microbial-derived glycolipids and lipopeptides: a review

et al. 2021

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Microbial biosurfactants are sustainable alternatives for synthetic counterparts, and display high biodegradability, environmental compatibility, and high selectivity. While previous reports have focussed on production yield, little attention has been paid on downstream processing of biosurfactants, a critical step that controls quality. Here we review methods for biosurfactant downstream processing with focus on glycolipids and lipopeptidesglycolipids and lipopeptides. Solvent extraction, foam fractionation, and sweep floc coagulation allow to reach a purity of 55-70%. While distillation can be implemented prematurely, methods like ultrafiltration and chromatography are used as final processing to recover 90-95% of biosurfactant with 78-95% of purity. We present the cheapest and most efficient downstream techniques for industries to achieve acceptable product quality. This paper puts forth the environmental applications of biosurfactants. We review applications in treating hydrophobic organic pollutants and heavy metals in soils and water. The removal efficiency of biosurfactants reaches 96%. Biosurfactants in the detergent industry, microbial enhanced oil recovery, and soil washing are also discussed.

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“…They are relevant in pharmaceuticals for the delivery of drugs and genes to target cells, the design of molecules to interact with components of the immune system, and as antimicrobial agents. Biocompatibility, low toxicity, and environmental friendliness are advantages that make them better options over synthetic surfactants [18,[24][25][26]. Biosurfactants have various innovative applications in the development of effective therapeutics which can come in handy at times of urgent need, such as during outbreaks or pandemics.…”

Section: Therapeuticsmentioning

confidence: 99%

Biosurfactants’ Potential Role in Combating COVID-19 and Similar Future Microbial Threats

et al. 2020

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During 2020, the world has experienced extreme vulnerability in the face of a disease outbreak. The coronavirus disease 2019 (COVID-19) pandemic discovered in China and rapidly spread across the globe, infecting millions, causing hundreds of thousands of deaths, and severe downturns in the economies of countries worldwide. Biosurfactants can play a significant role in the prevention, control and treatment of diseases caused by these pathogenic agents through various therapeutic, pharmaceutical, environmental and hygiene approaches. Biosurfactants have the potential to inhibit microbial species with virulent intrinsic characteristics capable of developing diseases with high morbidity and mortality, as well as interrupting their spread through environmental and hygiene interventions. This is possible due to their antimicrobial activity, ability to interact with cells forming micelles and to interact with the immune system, and compatibility with relevant processes such as nanoparticle synthesis. They, therefore, can be applied in developing innovative and more effective pharmaceutical, therapeutics, sustainable and friendly environmental management approaches, less toxic formulations, and more efficient cleaning agents. These approaches can be easily integrated into relevant product development pipelines and implemented as measures for combating and managing pandemics. This review examines the potential approaches of biosurfactants as useful molecules in fighting microbial pathogens both known and previously unknown, such as COVID-19.

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Biosurfactants: the next generation biomolecules for diverse applications

Cited by 39 publications

References 209 publications

Tapping the Role of Microbial Biosurfactants in Pesticide Remediation: An Eco-Friendly Approach for Environmental Sustainability

Tapping the Role of Microbial Biosurfactants in Pesticide Remediation: An Eco-Friendly Approach for Environmental Sustainability

Extraction, purification and applications of biosurfactants based on microbial-derived glycolipids and lipopeptides: a review

Biosurfactants’ Potential Role in Combating COVID-19 and Similar Future Microbial Threats

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